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CHICK:BIR

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ITA (synonyms: IAP1)
Protein Name(s) Inhibitor of apoptosis protein

IAP Inhibitor of T-cell apoptosis protein

External Links
UniProt Q90660
EMBL U27466
AF008592
RefSeq NP_001007823.1
UniGene Gga.21826
ProteinModelPortal Q90660
SMR Q90660
STRING 9031.ENSGALP00000035646
MEROPS I32.006
PaxDb Q90660
PRIDE Q90660
GeneID 374012
KEGG gga:374012
CTD 329
eggNOG NOG243347
HOGENOM HOG000232059
HOVERGEN HBG004848
InParanoid Q90660
KO K16060
OrthoDB EOG78H3TF
PhylomeDB Q90660
TreeFam TF105356
Reactome REACT_274339
REACT_300602
REACT_359284
NextBio 20813540
PRO PR:Q90660
Proteomes UP000000539
ExpressionAtlas Q90660
GO GO:0005737
GO:0005634
GO:0008270
GO:0006915
GO:0043066
Gene3D 1.10.1170.10
1.10.533.10
InterPro IPR001370
IPR001315
IPR011029
IPR001841
Pfam PF00653
PF00619
SMART SM00238
SM00114
SM00184
SUPFAM SSF47986
PROSITE PS01282
PS50143
PS50209
PS50089

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:9372964[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P29452

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:9372964[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1990001

inhibition of cysteine-type endopeptidase activity involved in apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260635
MGI:MGI:107572
PANTHER:PTN000799425

P

Seeded From UniProt

complete

enables

GO:0061630

ubiquitin protein ligase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015247
FB:FBgn0260635
PANTHER:PTN000799425
UniProtKB:P98170

F

Seeded From UniProt

complete

involved_in

GO:0060546

negative regulation of necroptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1197007
MGI:MGI:1197009
PANTHER:PTN000740861

P

Seeded From UniProt

complete

enables

GO:0043027

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015247
FB:FBgn0260635
PANTHER:PTN000799425

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260635
MGI:MGI:107572
MGI:MGI:1203517
PANTHER:PTN000005166
RGD:620692
UniProtKB:O15392
UniProtKB:P98170
UniProtKB:Q13489
UniProtKB:Q13490
UniProtKB:Q96CA5

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260635
PANTHER:PTN000005166
PomBase:SPCC962.02c
RGD:620690
RGD:620692
UniProtKB:O15392
UniProtKB:P98170
UniProtKB:Q13489
UniProtKB:Q13490
UniProtKB:Q96CA5

C

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0061630

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001315

P

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 You, M et al. (1997) ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol. 17 7328-41 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page