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CHICK:AT2A2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ATP2A2
Protein Name(s) Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

SERCA2 SR Ca(2+)-ATPase 2 Calcium pump 2 Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform Endoplasmic reticulum class 1/2 Ca(2+) ATPase

External Links
UniProt Q03669
EMBL M66385
PIR A40812
RefSeq NP_001258902.1
NP_001258903.1
UniGene Gga.42608
ProteinModelPortal Q03669
SMR Q03669
STRING 9031.ENSGALP00000038523
PaxDb Q03669
PRIDE Q03669
GeneID 396446
KEGG gga:396446
CTD 488
eggNOG COG0474
HOGENOM HOG000265621
HOVERGEN HBG105648
InParanoid Q03669
KO K05853
OMA MESAFAR
OrthoDB EOG73Z2SF
PhylomeDB Q03669
TreeFam TF300651
Reactome REACT_289873
REACT_313123
REACT_324147
PRO PR:Q03669
Proteomes UP000000539
GO GO:0090534
GO:0014704
GO:0014801
GO:0097470
GO:0016529
GO:0033017
GO:0005524
GO:0005509
GO:0005388
GO:0006816
GO:1903515
GO:0006874
GO:0006984
GO:0045822
GO:0006996
GO:0032470
GO:1903233
GO:0010882
GO:0002026
GO:0055119
GO:0042493
GO:0070296
GO:0033292
GO:0014883
Gene3D 1.20.1110.10
2.70.150.10
3.40.1110.10
InterPro IPR006068
IPR004014
IPR023299
IPR018303
IPR023298
IPR008250
IPR023214
IPR005782
IPR001757
IPR030327
PANTHER PTHR24093:SF234
Pfam PF00689
PF00690
PF00122
PF00702
PRINTS PR00119
PR00120
SMART SM00831
SUPFAM SSF56784
SSF81660
TIGRFAMs TIGR01116
TIGR01494
PROSITE PS00154

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042493

response to drug

PMID:11341768[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

CHEBI:8925

P

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

PMID:11341768[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11507

P

Seeded From UniProt

complete

involved_in

GO:0070588

calcium ion transmembrane transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000643382
RGD:2174
UniProtKB:P16615

P

Seeded From UniProt

complete

part_of

GO:0033017

sarcoplasmic reticulum membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105058
PANTHER:PTN000643383

C

Seeded From UniProt

complete

enables

GO:0008553

proton-exporting ATPase activity, phosphorylative mechanism

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001943383
PomBase:SPAC1071.10c
PomBase:SPCC1020.01c
SGD:S000002976
SGD:S000005957
TAIR:locus:2020372
TAIR:locus:2044450
TAIR:locus:2165600
UniProtKB:A0A1D8PJ01

F

Seeded From UniProt

complete

involved_in

GO:0006874

cellular calcium ion homeostasis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0263006
MGI:MGI:88110
PANTHER:PTN000643382
UniProtKB:P16615
WB:WBGene00004736
ZFIN:ZDB-GENE-020905-1

P

Seeded From UniProt

complete

enables

GO:0005388

calcium-transporting ATPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88110
PANTHER:PTN000643382
RGD:2174
RGD:621293
TAIR:locus:2201916
UniProtKB:O14983
UniProtKB:P16615
WB:WBGene00004736

F

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005388

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005388

P

Seeded From UniProt

complete

involved_in

GO:1902600

proton transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008553

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023299

F

Seeded From UniProt

complete

enables

GO:0005388

calcium-transporting ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005782
InterPro:IPR030332

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030332

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030332

C

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005782

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001757
InterPro:IPR005782
InterPro:IPR030332

C

Seeded From UniProt

complete

part_of

GO:0033017

sarcoplasmic reticulum membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030332

C

Seeded From UniProt

complete

involved_in

GO:0070588

calcium ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030332

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016529

sarcoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0703

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0109

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

part_of

GO:0033017

sarcoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0241

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Obata, K et al. (2001) Role of FK506-binding protein 12 in development of the chick embryonic heart. Biochem. Biophys. Res. Commun. 283 613-20 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page