CHICK:AGO3

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	AGO3 (synonyms: EIF2C3)
Protein Name(s)	Protein argonaute-3 (ECO:0000255 with HAMAP-Rule:MF_03032) Argonaute3 (ECO:0000255 with HAMAP-Rule:MF_03032) Argonaute RISC catalytic component 3 Eukaryotic translation initiation factor 2C 3 (ECO:0000255 with HAMAP-Rule:MF_03032) eIF-2C 3 (ECO:0000255 with HAMAP-Rule:MF_03032) eIF2C 3 (ECO:0000255 with HAMAP-Rule:MF_03032)
External Links
UniProt	Q5ZLG4
EMBL	AJ719770
RefSeq	NP_001026071.1
UniGene	Gga.22391
ProteinModelPortal	Q5ZLG4
SMR	Q5ZLG4
STRING	9031.ENSGALP00000003521
PaxDb	Q5ZLG4
PRIDE	Q5ZLG4
GeneID	419628
KEGG	gga:419628
CTD	192669
eggNOG	NOG279895
HOGENOM	HOG000116043
InParanoid	Q5ZLG4
KO	K11593
PhylomeDB	Q5ZLG4
NextBio	20822658
PRO	PR:Q5ZLG4
Proteomes	UP000000539
GO	GO:0000932 GO:0035068 GO:0016442 GO:0035198 GO:0006402 GO:0035278 GO:0072091
Gene3D	3.30.420.10
HAMAP	MF_03032
InterPro	IPR028603 IPR014811 IPR003100 IPR003165 IPR012337
Pfam	PF08699 PF02170 PF02171
SMART	SM00949 SM00950
SUPFAM	SSF101690 SSF53098
PROSITE	PS50821 PS50822

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0090624	endoribonuclease activity, cleaving miRNA-paired mRNA	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H9G7	F		Seeded From UniProt	complete
enables	GO:0004521	endoribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H9G7	F		Seeded From UniProt	complete
involved_in	GO:0035278	miRNA mediated inhibition of translation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H9G7	P		Seeded From UniProt	complete
involved_in	GO:0006402	mRNA catabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H9G7	P		Seeded From UniProt	complete
involved_in	GO:0035279	mRNA cleavage involved in gene silencing by miRNA	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0090624	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004519	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004521	P		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003165 InterPro:IPR036397	F		Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028603	P		Seeded From UniProt	complete
involved_in	GO:0072091	regulation of stem cell proliferation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028603	P		Seeded From UniProt	complete
involved_in	GO:0035278	miRNA mediated inhibition of translation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000107558	P		Seeded From UniProt	complete
part_of	GO:0016442	RISC complex	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000107558	C		Seeded From UniProt	complete
part_of	GO:0035068	micro-ribonucleoprotein complex	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000107558	C		Seeded From UniProt	complete
enables	GO:0035198	miRNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000107558	F		Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0943	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
involved_in	GO:0006417	regulation of translation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0810	P		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
part_of	GO:0000932	P-body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0230	C		Seeded From UniProt	complete
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References

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