CANLF:CUBN

Species (Taxon ID)	Canis lupus familiaris (Dog) (Canis familiaris). (9615)
Gene Name(s)	CUBN
Protein Name(s)	Cubilin
External Links
UniProt	Q9TU53
EMBL	AF137068
RefSeq	NP_001003148.1
UniGene	Cfa.3631
ProteinModelPortal	Q9TU53
STRING	9615.ENSCAFP00000006833
PaxDb	Q9TU53
PRIDE	Q9TU53
GeneID	403767
KEGG	cfa:403767
CTD	8029
eggNOG	KOG3714 ENOG410ZPX7
HOGENOM	HOG000049236
HOVERGEN	HBG080357
InParanoid	Q9TU53
KO	K14616
Proteomes	UP000002254
GO	GO:0016324 GO:0010008 GO:0005765 GO:0005509 GO:0031419 GO:0004872 GO:0008203 GO:0015031 GO:0006898
Gene3D	2.60.120.290
InterPro	IPR000859 IPR028876 IPR001881 IPR013032 IPR000742 IPR000152 IPR018097 IPR024731 IPR009030
PANTHER	PTHR10127:SF645
Pfam	PF00431 PF00008 PF12947 PF07645
SMART	SM00042 SM00181 SM00179
SUPFAM	SSF49854 SSF57184
PROSITE	PS00010 PS01180 PS00022 PS01186 PS50026 PS01187

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0016324	apical plasma membrane	PMID:6321516	ECO:0000314			C		Figure 7 shows that an antibody for the intrinsic factor-cobalamin complex (IF-cbl) [now known and cubam or cubilin and amnionless] is found at the microvillus pits of the apical membrane of ileum cells.	complete CACAO 9853
part_of	GO:0031526	brush border membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O70244	C		Seeded From UniProt	complete
enables	GO:0008144	drug binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O70244	F		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	PMID:6321516	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001881 InterPro:IPR018097	F		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0458	C		Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0031419	cobalamin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0846	F		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C		Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0153	P		Seeded From UniProt	complete
involved_in	GO:0008202	steroid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0753	P		Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0157	C		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C		Seeded From UniProt	complete
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References

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