BOVIN:WASL

Species (Taxon ID)	Bos taurus (Bovine). (9913)
Gene Name(s)	WASL
Protein Name(s)	Neural Wiskott-Aldrich syndrome protein N-WASP
External Links
UniProt	Q95107
EMBL	D67066
PIR	S72273
RefSeq	NP_776644.1
UniGene	Bt.359
ProteinModelPortal	Q95107
SMR	Q95107
IntAct	Q95107
STRING	9913.ENSBTAP00000006094
PaxDb	Q95107
PRIDE	Q95107
Ensembl	ENSBTAT00000006094
GeneID	281577
KEGG	bta:281577
CTD	8976
eggNOG	NOG270974
GeneTree	ENSGT00730000110895
HOGENOM	HOG000143378
HOVERGEN	HBG000222
InParanoid	Q95107
KO	K05747
OMA	DAPNGPN
OrthoDB	EOG7FJH20
TreeFam	TF316736
Reactome	REACT_211475 REACT_211504 REACT_216118 REACT_226967 REACT_259381
NextBio	20805526
Proteomes	UP000009136
ExpressionAtlas	Q95107
GO	GO:0030478 GO:0070062 GO:0030027 GO:0005634 GO:0042802 GO:0007015 GO:0034629 GO:0007067 GO:0032880 GO:0006355 GO:0009617 GO:0051653 GO:0006351
Gene3D	2.30.29.30 3.90.810.10
InterPro	IPR000095 IPR030214 IPR011993 IPR011026 IPR000697 IPR003124
PANTHER	PTHR12779:SF3
Pfam	PF00786 PF00568 PF02205
SMART	SM00285 SM00461 SM00246
SUPFAM	SSF47912
PROSITE	PS50108 PS50229 PS51082

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00401	C	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00401	P	Seeded From UniProt	complete
involved_in	GO:0030041	actin filament polymerization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00401	P	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q91YD9	P	Seeded From UniProt	complete
involved_in	GO:0051666	actin cortical patch localization	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001506182 SGD:S000004329 SGD:S000005707	P	Seeded From UniProt	complete
involved_in	GO:0051127	positive regulation of actin nucleation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001506182 PomBase:SPBC13E7.09	P	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0243516 PANTHER:PTN001506182	F	Seeded From UniProt	complete
part_of	GO:0030479	actin cortical patch	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001506182 PomBase:SPAC4F10.15c PomBase:SPBC13E7.09 SGD:S000004329 SGD:S000005707 UniProtKB:A0A1D8PU03	C	Seeded From UniProt	complete
involved_in	GO:0030048	actin filament-based movement	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105059 MGI:MGI:2178801 PANTHER:PTN001506182	P	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001506182 PomBase:SPAC4F10.15c SGD:S000004329 UniProtKB:A0A1D8PU03	P	Seeded From UniProt	complete
part_of	GO:0005884	actin filament	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2178801 PANTHER:PTN001506182 RGD:620887 UniProtKB:P42768	C	Seeded From UniProt	complete
involved_in	GO:0000147	actin cortical patch assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001506182 PomBase:SPAC4F10.15c PomBase:SPBC13E7.09	P	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:10995436^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q95107	F	Seeded From UniProt	complete
involved_in	GO:2000402	negative regulation of lymphocyte migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	P	Seeded From UniProt	complete
involved_in	GO:1903526	negative regulation of membrane tubulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	P	Seeded From UniProt	complete
involved_in	GO:0030041	actin filament polymerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00401 ensembl:ENSP00000223023	C	Seeded From UniProt	complete
involved_in	GO:0030036	actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	C	Seeded From UniProt	complete
involved_in	GO:0009617	response to bacterium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
involved_in	GO:0051653	spindle localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
involved_in	GO:0034629	cellular protein-containing complex localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
involved_in	GO:0032880	regulation of protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	P	Seeded From UniProt	complete
part_of	GO:0030478	actin cap	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91YD9 ensembl:ENSMUSP00000031695	C	Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003124 InterPro:IPR030214	F	Seeded From UniProt	complete
involved_in	GO:0007015	actin filament organization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011026 InterPro:IPR030214	P	Seeded From UniProt	complete
involved_in	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030214	P	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206 UniProtKB-SubCell:SL-0090	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0009	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Rohatgi, R et al. (2000) Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J. Cell Biol. 150 1299-310 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10995436-2] Rohatgi, R et al. (2000) Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J. Cell Biol. 150 1299-310 PubMed GONUTS page

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BOVIN:WASL

Contents

Annotations

Notes

References

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