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BOVIN:TAU
Contents
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0006468 |
protein phosphorylation |
ECO:0000314 |
P |
Figure 1 and 2 showed the electrophoresis of the results of dephosphorylating tau in different conditions and reversing that process, respectively. The analysis revealed a change in eletrophoretic mobility, showing that tau can exist in two separate states that are readily interconvertible by phosphorylation and dephosphorylation. |
complete | |||||
part_of |
GO:0030425 |
dendrite |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:1905689 |
positive regulation of diacylglycerol kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P52824) |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97175 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031175 |
neuron projection development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000161190 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008017 |
microtubule binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0266579 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000226 |
microtubule cytoskeleton organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0266579 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0048018 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2001020 |
regulation of response to DNA damage stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904428 |
negative regulation of tubulin deacetylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900034 |
regulation of cellular response to heat |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0097386 |
glial cell projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060632 |
regulation of microtubule-based movement |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048675 |
axon extension |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0047497 |
mitochondrion transport along microtubule |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045773 |
positive regulation of axon extension |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0045121 |
membrane raft |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0044297 |
cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032387 |
negative regulation of intracellular transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030424 |
axon |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0015630 |
microtubule cytoskeleton |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008088 |
axo-dendritic transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008017 |
microtubule binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007628 |
adult walking behavior |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007409 |
axonogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005930 |
axoneme |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001764 |
neuron migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000226 |
microtubule cytoskeleton organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10637 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2001020 |
regulation of response to DNA damage stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1990000 |
amyloid fibril formation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904428 |
negative regulation of tubulin deacetylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903829 |
positive regulation of cellular protein localization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903748 |
negative regulation of establishment of protein localization to mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902474 |
positive regulation of protein localization to synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1901216 |
positive regulation of neuron death |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900034 |
regulation of cellular response to heat |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0099609 |
microtubule lateral binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097435 |
supramolecular fiber organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0097418 |
neurofibrillary tangle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090258 |
negative regulation of mitochondrial fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0071813 |
lipoprotein particle binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070507 |
regulation of microtubule cytoskeleton organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0051879 |
Hsp90 protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0051087 |
chaperone binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050848 |
regulation of calcium-mediated signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050808 |
synapse organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048018 |
receptor ligand activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045773 |
positive regulation of axon extension |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0045298 |
tubulin complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0044297 |
cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0036477 |
somatodendritic compartment |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0036464 |
cytoplasmic ribonucleoprotein granule |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0034399 |
nuclear periphery |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0034185 |
apolipoprotein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0033673 |
negative regulation of kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032930 |
positive regulation of superoxide anion generation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031116 |
positive regulation of microtubule polymerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031110 |
regulation of microtubule polymerization or depolymerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030673 |
axolemma |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0030426 |
growth cone |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0030425 |
dendrite |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0030424 |
axon |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0017124 |
SH3 domain binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016607 |
nuclear speck |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0015630 |
microtubule cytoskeleton |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010917 |
negative regulation of mitochondrial membrane potential |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010629 |
negative regulation of gene expression |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010506 |
regulation of autophagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008017 |
microtubule binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007613 |
memory |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000226 |
microtubule cytoskeleton organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P10636 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008017 |
microtubule binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0015631 |
tubulin binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005874 |
microtubule |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030425 |
dendrite |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lindwall, G & Cole, RD (1984) Phosphorylation affects the ability of tau protein to promote microtubule assembly. J. Biol. Chem. 259 5301-5 PubMed GONUTS page
- ↑ Tu-Sekine, B & Raben, DM (2012) Dual regulation of diacylglycerol kinase (DGK)-θ: polybasic proteins promote activation by phospholipids and increase substrate affinity. J. Biol. Chem. 287 41619-27 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
a
c
m
- Mammalia
- GO:0016020 ! membrane
- GO:0045121 ! membrane raft
- GO:0007613 ! memory
- Metazoa
- GO:0005874 ! microtubule
- GO:0000226 ! microtubule cytoskeleton organization
- GO:0099609 ! microtubule lateral binding
- GO:0008017 ! microtubule binding
- GO:0015630 ! microtubule cytoskeleton
- GO:0047497 ! mitochondrion transport along microtubule
n
- GO:0010917 ! negative regulation of mitochondrial membrane potential
- GO:0010629 ! negative regulation of gene expression
- GO:0033673 ! negative regulation of kinase activity
- GO:1903748 ! negative regulation of establishment of protein localization to mitochondrion
- GO:1904428 ! negative regulation of tubulin deacetylation
- GO:0090258 ! negative regulation of mitochondrial fission
- GO:0032387 ! negative regulation of intracellular transport
- GO:0097418 ! neurofibrillary tangle
- GO:0043025 ! neuronal cell body
- GO:0001764 ! neuron migration
- GO:0043005 ! neuron projection
- GO:0031175 ! neuron projection development
- GO:0034399 ! nuclear periphery
- GO:0016607 ! nuclear speck
- GO:0005634 ! nucleus
o
p
- Pecora
- GO:0005886 ! plasma membrane
- GO:0045773 ! positive regulation of axon extension
- GO:0031116 ! positive regulation of microtubule polymerization
- GO:0032930 ! positive regulation of superoxide anion generation
- GO:1903829 ! positive regulation of protein localization
- GO:1902474 ! positive regulation of protein localization to synapse
- GO:1905689 ! positive regulation of diacylglycerol kinase activity
- GO:0014069 ! postsynaptic density
- GO:0051087 ! protein-folding chaperone binding
- GO:0042803 ! protein homodimerization activity
- GO:0019901 ! protein kinase binding
- GO:0006468 ! protein phosphorylation
r
- GO:0048018 ! receptor ligand activity
- GO:0070507 ! regulation of microtubule cytoskeleton organization
- GO:0010469 ! regulation of signaling receptor activity
- GO:1900034 ! regulation of cellular response to heat
- GO:0060632 ! regulation of microtubule-based movement
- GO:0050848 ! regulation of calcium-mediated signaling
- GO:0010506 ! regulation of autophagy
- GO:0031110 ! regulation of microtubule polymerization or depolymerization
- Ruminantia
s