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BOVIN:MA2B1

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) MAN2B1 (synonyms: MANB)
Protein Name(s) Lysosomal alpha-mannosidase

Laman Lysosomal acid alpha-mannosidase Mannosidase alpha class 2B member 1 Mannosidase alpha-B Lysosomal alpha-mannosidase A peptide Lysosomal alpha-mannosidase B peptide Lysosomal alpha-mannosidase C peptide Lysosomal alpha-mannosidase D peptide Lysosomal alpha-mannosidase E peptide

External Links
UniProt Q29451
EMBL L31373
U97694
U97686
U97687
U97688
U97689
U97690
U97691
U97692
U97693
DAAA02019388
RefSeq NP_776986.2
UniGene Bt.4622
PDB 1O7D
PDBsum 1O7D
STRING 9913.ENSBTAP00000008193
ChEMBL CHEMBL1932902
CAZy GH38
PRIDE Q29451
Ensembl ENSBTAT00000008193
GeneID 282272
KEGG bta:282272
CTD 4125
eggNOG COG0383
GeneTree ENSGT00510000046304
HOGENOM HOG000007676
HOVERGEN HBG052391
InParanoid Q29451
KO K12311
OMA NMQLTVL
OrthoDB EOG786H2P
TreeFam TF313840
EvolutionaryTrace Q29451
NextBio 20806083
Proteomes UP000009136
ExpressionAtlas Q29451
GO GO:0005764
GO:0004559
GO:0030246
GO:0008270
GO:0007611
GO:0006013
Gene3D 1.20.1270.50
2.60.40.1180
3.20.110.10
InterPro IPR011013
IPR011330
IPR013780
IPR027291
IPR011682
IPR015341
IPR000602
IPR028995
Pfam PF09261
PF01074
PF07748
SMART SM00872
SUPFAM SSF74650
SSF88688
SSF88713

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006517

protein deglycosylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0011740
FB:FBgn0026616
PANTHER:PTN002480870

P

Seeded From UniProt

complete

involved_in

GO:0006013

mannose metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107286
PANTHER:PTN002480870
RGD:1308840

P

Seeded From UniProt

complete

part_of

GO:0005774

vacuolar membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000176485
UniProtKB:P94078
UniProtKB:Q8LPJ3

C

Seeded From UniProt

complete

enables

GO:0004559

alpha-mannosidase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0027611
MGI:MGI:107286
PANTHER:PTN002480870
RGD:1308840
RGD:3039
TAIR:locus:2147855
UniProtKB:P94078
dictyBase:DDB_G0292206

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011013
InterPro:IPR011330

F

Seeded From UniProt

complete

enables

GO:0004559

alpha-mannosidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000602
InterPro:IPR011682
InterPro:IPR015341
InterPro:IPR037094

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011013
InterPro:IPR011330

P

Seeded From UniProt

complete

involved_in

GO:0006013

mannose metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000602
InterPro:IPR011682
InterPro:IPR015341
InterPro:IPR037094

P

Seeded From UniProt

complete

enables

GO:0030246

carbohydrate binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011013

F

Seeded From UniProt

complete

enables

GO:0004559

alpha-mannosidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.24

F

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0458
UniProtKB-SubCell:SL-0158

C

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page