BOVIN:CASK

Species (Taxon ID)	Bos taurus (Bovine). (9913)
Gene Name(s)	CSN3 (synonyms: CSN10, CSNK)
Protein Name(s)	Kappa-casein Casoxin-C Casoxin-6 Casoxin-A Casoxin-B Casoplatelin
External Links
UniProt	P02668
EMBL	X00565 M36641 X14907 X14908 AY380228 AY380229 BC102120 K01085 AF123250 AF123251 AF105260 M38333 AF041482 U84250 U84251
PIR	S02076
RefSeq	NP_776719.1
UniGene	Bt.49421
DisProt	DP00192
BioGrid	159044
IntAct	P02668
MINT	MINT-7258912
Allergome	10200 167 2737
UniCarbKB	P02668
PaxDb	P02668
PRIDE	P02668
Ensembl	ENSBTAT00000028685
GeneID	281728
KEGG	bta:281728
CTD	1448
eggNOG	NOG40632
GeneTree	ENSGT00390000009184
HOVERGEN	HBG005246
InParanoid	P02668
KO	K17282
OrthoDB	EOG7MWH09
TreeFam	TF338369
NextBio	20805648
PMAP-CutDB	P02668
Proteomes	UP000009136
GO	GO:0005615 GO:0042802 GO:0007595 GO:0050821
InterPro	IPR000117
PANTHER	PTHR11470
Pfam	PF00997
PIRSF	PIRSF002374

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0032355	response to estradiol	PMID:3585228^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0001911) happens_during:(GO:0007595)	Seeded From UniProt	complete
involved_in	GO:0032570	response to progesterone	PMID:3585228^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0001911) happens_during:(GO:0007595)	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	PMID:5168866^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001911)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9112130^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1903496	response to 11-deoxycorticosterone	PMID:3585228^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	happens_during:(GO:0007595) occurs_in:(UBERON:0001911)	Seeded From UniProt	complete
involved_in	GO:1903494	response to dehydroepiandrosterone	PMID:3585228^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	happens_during:(GO:0007595) occurs_in:(UBERON:0001911)	Seeded From UniProt	complete
part_of	GO:0005796	Golgi lumen	PMID:5168866^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001911)	Seeded From UniProt	complete
enables	GO:0035375	zymogen binding	PMID:8186264^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P00750	F		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	PMID:8186264^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0035375	zymogen binding	PMID:8186264^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q28198	F		Seeded From UniProt	complete
enables	GO:0035375	zymogen binding	PMID:8186264^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9MZF7	F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:8186264^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:3549815^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000895253 UniProtKB:P07498	P		Seeded From UniProt	complete
involved_in	GO:0007595	lactation	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107461 PANTHER:PTN000895253 UniProtKB:P07498	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000895253 UniProtKB:P02668 UniProtKB:P07498	C		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:19754881^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P02668	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000117	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Shamay, A et al. (1987) Inhibition of casein and fat synthesis and alpha-lactalbumin secretion by progesterone in explants from bovine lactating mammary glands. J. Endocrinol. 113 81-8 PubMed GONUTS page
↑ ^2.0 ^2.1 Beery, KE et al. (1971) Formation of casein micelles in golgi vesicles of mammary tissue. J. Dairy Sci. 54 911-2 PubMed GONUTS page
↑ Keys, JE et al. (1997) Bovine mammary explant versus primary cell cultures: effect of bovine somatotropin and insulin-like growth factor-I on DNA content and protein synthesis. In Vitro Cell. Dev. Biol. Anim. 33 206-11 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Heegaard, CW et al. (1994) The plasminogen activation system in bovine milk: differential localization of tissue-type plasminogen activator and urokinase in milk fractions is caused by binding to casein and urokinase receptor. Biochim. Biophys. Acta 1222 45-55 PubMed GONUTS page
↑ Cohick, WS et al. (1986) Effects of intake and postruminal casein infusion on performance and concentrations of hormones in plasma of lactating cows. J. Dairy Sci. 69 3022-31 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Hudson, SA et al. (2009) The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds. FEBS J. 276 5960-72 PubMed GONUTS page

[PMID:3585228-1] 1.0 ^1.1 ^1.2 ^1.3 Shamay, A et al. (1987) Inhibition of casein and fat synthesis and alpha-lactalbumin secretion by progesterone in explants from bovine lactating mammary glands. J. Endocrinol. 113 81-8 PubMed GONUTS page

[PMID:5168866-2] 2.0 ^2.1 Beery, KE et al. (1971) Formation of casein micelles in golgi vesicles of mammary tissue. J. Dairy Sci. 54 911-2 PubMed GONUTS page

[PMID:9112130-3] Keys, JE et al. (1997) Bovine mammary explant versus primary cell cultures: effect of bovine somatotropin and insulin-like growth factor-I on DNA content and protein synthesis. In Vitro Cell. Dev. Biol. Anim. 33 206-11 PubMed GONUTS page

[PMID:8186264-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Heegaard, CW et al. (1994) The plasminogen activation system in bovine milk: differential localization of tissue-type plasminogen activator and urokinase in milk fractions is caused by binding to casein and urokinase receptor. Biochim. Biophys. Acta 1222 45-55 PubMed GONUTS page

[PMID:3549815-5] Cohick, WS et al. (1986) Effects of intake and postruminal casein infusion on performance and concentrations of hormones in plasma of lactating cows. J. Dairy Sci. 69 3022-31 PubMed GONUTS page

[PMID:21873635-6] 6.0 ^6.1 ^6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19754881-7] Hudson, SA et al. (2009) The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds. FEBS J. 276 5960-72 PubMed GONUTS page

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BOVIN:CASK

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