BOVIN:ATPB

Species (Taxon ID)	Bos taurus (Bovine). (9913)
Gene Name(s)	ATP5B
Protein Name(s)	ATP synthase subunit beta, mitochondrial
External Links
UniProt	P00829
EMBL	M20929 BC116099 X05605
PIR	A28717
RefSeq	NP_786990.1
UniGene	Bt.4431
PDB	1BMF 1COW 1E1Q 1E1R 1E79 1EFR 1H8E 1H8H 1NBM 1OHH 1QO1 1W0J 1W0K 2CK3 2JDI 2JIZ 2JJ1 2JJ2 2V7Q 2W6E 2W6F 2W6G 2W6H 2W6I 2W6J 2WSS 2XND 4ASU 4TSF 4TT3
PDBsum	1BMF 1COW 1E1Q 1E1R 1E79 1EFR 1H8E 1H8H 1NBM 1OHH 1QO1 1W0J 1W0K 2CK3 2JDI 2JIZ 2JJ1 2JJ2 2V7Q 2W6E 2W6F 2W6G 2W6H 2W6I 2W6J 2WSS 2XND 4ASU 4TSF 4TT3
ProteinModelPortal	P00829
SMR	P00829
DIP	DIP-35476N
IntAct	P00829
MINT	MINT-5006882
BindingDB	P00829
ChEMBL	CHEMBL612444
PaxDb	P00829
PRIDE	P00829
Ensembl	ENSBTAT00000017710
GeneID	327675
KEGG	bta:327675
CTD	506
eggNOG	COG0055
GeneTree	ENSGT00550000074800
HOGENOM	HOG000009605
HOVERGEN	HBG004307
InParanoid	P00829
KO	K02133
OMA	RWPIHRK
OrthoDB	EOG73V6K6
TreeFam	TF105640
Reactome	REACT_212639 REACT_214581 REACT_215731
EvolutionaryTrace	P00829
NextBio	20810140
Proteomes	UP000009136
GO	GO:0009986 GO:0070062 GO:0042645 GO:0005753 GO:0005634 GO:0005886 GO:0045261 GO:0005524 GO:0046933 GO:0046961 GO:0001525 GO:0006200 GO:0015991 GO:0015986 GO:0006629 GO:0006933 GO:0001649 GO:0051453
Gene3D	1.10.1140.10 3.40.50.300
HAMAP	MF_01347
InterPro	IPR003593 IPR020003 IPR005722 IPR000793 IPR000194 IPR004100 IPR024034 IPR027417
Pfam	PF00006 PF00306 PF02874
SMART	SM00382
SUPFAM	SSF47917 SSF50615 SSF52540
TIGRFAMs	TIGR01039
PROSITE	PS00152

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005753	mitochondrial proton-transporting ATP synthase complex	PMID:1827992^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	PMID:17510399^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005753	mitochondrial proton-transporting ATP synthase complex	PMID:17570365^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0046933	P	Seeded From UniProt	complete
involved_in	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0046933	P	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	P	Seeded From UniProt	complete
involved_in	GO:0051453	regulation of intracellular pH	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	P	Seeded From UniProt	complete
enables	GO:0046961	proton-transporting ATPase activity, rotational mechanism	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	F	Seeded From UniProt	complete
enables	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	F	Seeded From UniProt	complete
part_of	GO:0045259	proton-transporting ATP synthase complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
involved_in	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	P	Seeded From UniProt	complete
enables	GO:0043532	angiostatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	F	Seeded From UniProt	complete
part_of	GO:0042645	mitochondrial nucleoid	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
enables	GO:0042288	MHC class I protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	F	Seeded From UniProt	complete
part_of	GO:0031966	mitochondrial membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
involved_in	GO:0006754	ATP biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
part_of	GO:0005753	mitochondrial proton-transporting ATP synthase complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06576 ensembl:ENSP00000262030	P	Seeded From UniProt	complete
involved_in	GO:0098761	cellular response to interleukin-7	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56480 ensembl:ENSMUSP00000026459	P	Seeded From UniProt	complete
involved_in	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56480 ensembl:ENSMUSP00000026459	P	Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56480 ensembl:ENSMUSP00000026459	P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56480 ensembl:ENSMUSP00000026459	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:V9HW31 ensembl:ENSP00000262030	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000194 InterPro:IPR020003	F	Seeded From UniProt	complete
involved_in	GO:0015986	ATP synthesis coupled proton transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005722	P	Seeded From UniProt	complete
part_of	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005722	C	Seeded From UniProt	complete
involved_in	GO:0046034	ATP metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004100 InterPro:IPR036121	P	Seeded From UniProt	complete
enables	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005722	F	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004100 InterPro:IPR036121	P	Seeded From UniProt	complete
involved_in	GO:0006754	ATP biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0066	P	Seeded From UniProt	complete
part_of	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0139	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C	Seeded From UniProt	complete
part_of	GO:0005743	mitochondrial inner membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0999 UniProtKB-SubCell:SL-0168	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Walker, JE et al. (1991) Identification of the subunits of F1F0-ATPase from bovine heart mitochondria. Biochemistry 30 5369-78 PubMed GONUTS page
↑ Chi, SL et al. (2007) Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase. Cancer Res. 67 4716-24 PubMed GONUTS page
↑ Chen, R et al. (2007) Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria. FEBS Lett. 581 3145-8 PubMed GONUTS page

[PMID:1827992-1] Walker, JE et al. (1991) Identification of the subunits of F1F0-ATPase from bovine heart mitochondria. Biochemistry 30 5369-78 PubMed GONUTS page

[PMID:17510399-2] Chi, SL et al. (2007) Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase. Cancer Res. 67 4716-24 PubMed GONUTS page

[PMID:17570365-3] Chen, R et al. (2007) Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria. FEBS Lett. 581 3145-8 PubMed GONUTS page

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BOVIN:ATPB

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