BACSU:DNAA

Species (Taxon ID)	Bacillus subtilis (strain 168). (224308)
Gene Name(s)	dnaA (synonyms: dnaH)
Protein Name(s)	Chromosomal replication initiator protein DnaA
External Links
UniProt	P05648
EMBL	X02369 D26185 AL009126 X12778 X12779
PIR	A22930
RefSeq	NP_387882.1
PDB	4TPS
PDBsum	4TPS
ProteinModelPortal	P05648
SMR	P05648
IntAct	P05648
MINT	MINT-188900
STRING	224308.BSU00010
EnsemblBacteria	CAB11777
GeneID	939978
KEGG	bsu:BSU00010
PATRIC	18971449
GenoList	BSU00010
eggNOG	COG0593
HOGENOM	HOG000235658
InParanoid	P05648
KO	K02313
OMA	SFETWIR
OrthoDB	EOG689HR1
PhylomeDB	P05648
BioCyc	BSUB:BSU00010-MONOMER
Proteomes	UP000001570
GO	GO:0005737 GO:0005524 GO:0003688 GO:0006270 GO:0006275
Gene3D	1.10.1750.10 3.40.50.300
HAMAP	MF_00377
InterPro	IPR003593 IPR001957 IPR020591 IPR018312 IPR013159 IPR013317 IPR024633 IPR027417 IPR010921
Pfam	PF00308 PF08299 PF11638
PRINTS	PR00051
SMART	SM00382 SM00760
SUPFAM	SSF48295 SSF52540
TIGRFAMs	TIGR00362
PROSITE	PS01008

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0006270	DNA replication initiation	PMID:2167836^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
	GO:0006270	DNA-dependent DNA replication initiation	PMID:2167836^[1]	ECO:0000314			P	Fig. 6	complete CACAO 2805
involved_in	GO:0006270	DNA replication initiation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000769352 UniProtKB:P05648	P	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10235 PANTHER:PTN001574578	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10235 PANTHER:PTN000769352 UniProtKB:P9WNW3	C	Seeded From UniProt	complete
enables	GO:0003688	DNA replication origin binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10235 PANTHER:PTN000769352 UniProtKB:P9WNW3	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:27281207^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P05648	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:21630458^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P05648	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001957 InterPro:IPR018312	F	Seeded From UniProt	complete
enables	GO:0003688	DNA replication origin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001957 InterPro:IPR018312	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001957 InterPro:IPR013159 InterPro:IPR018312	F	Seeded From UniProt	complete
involved_in	GO:0006270	DNA replication initiation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001957 InterPro:IPR013159 InterPro:IPR018312	P	Seeded From UniProt	complete
involved_in	GO:0006275	regulation of DNA replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001957 InterPro:IPR013159 InterPro:IPR018312	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010921 InterPro:IPR013159	F	Seeded From UniProt	complete
enables	GO:0003688	DNA replication origin binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000084164	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000084164	F	Seeded From UniProt	complete
involved_in	GO:0006270	DNA replication initiation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000084164	P	Seeded From UniProt	complete
involved_in	GO:0006275	regulation of DNA replication	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000084164	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000084164	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Moriya, S et al. (1990) Isolation of a dnaA mutant of Bacillus subtilis defective in initiation of replication: amount of DnaA protein determines cells' initiation potential. EMBO J. 9 2905-10 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Richardson, TT et al. (2016) The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding. Nature 534 412-6 PubMed GONUTS page
↑ Marchadier, E et al. (2011) An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach. Proteomics 11 2981-91 PubMed GONUTS page

[PMID:2167836-1] 1.0 ^1.1 Moriya, S et al. (1990) Isolation of a dnaA mutant of Bacillus subtilis defective in initiation of replication: amount of DnaA protein determines cells' initiation potential. EMBO J. 9 2905-10 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:27281207-3] Richardson, TT et al. (2016) The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding. Nature 534 412-6 PubMed GONUTS page

[PMID:21630458-4] Marchadier, E et al. (2011) An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach. Proteomics 11 2981-91 PubMed GONUTS page

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BACSU:DNAA

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