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BACSG:AK

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Species (Taxon ID) Bacillus sp. (strain MGA3). (126782)
Gene Name(s) lysC
Protein Name(s) Aspartokinase 2

Aspartate kinase 2 Aspartokinase II

External Links
UniProt Q59229
EMBL M93419
ProteinModelPortal Q59229
GO GO:0016597
GO:0004072
GO:0005524
GO:0019877
Gene3D G3DSA:3.40.1160.10
InterPro IPR002912
IPR001048
IPR005260
IPR001341
IPR018042
Pfam PF00696
PF01842
PIRSF PIRSF000726
SUPFAM SSF53633
TIGRFAMs TIGR00656
TIGR00657
PROSITE PS00324

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004072

aspartate kinase activity

PMID:19060158[1]

ECO:0000314

F

In Fig 3 when the gene lysC is over expressed the aspartate kinase activity increases over 40x compared to the control strain.

complete
CACAO 4685

enables

GO:0004072

aspartate kinase activity

PMID:19060158[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004072

aspartate kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001341
InterPro:IPR005260
InterPro:IPR018042

F

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001341
InterPro:IPR018042

P

Seeded From UniProt

complete

involved_in

GO:0009089

lysine biosynthetic process via diaminopimelate

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005260

P

Seeded From UniProt

complete

enables

GO:0004072

aspartate kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.2.4

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

involved_in

GO:0019877

diaminopimelate biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0220

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0028

P

Seeded From UniProt

complete

involved_in

GO:0009085

lysine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0457

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0009088

threonine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00050

P

Seeded From UniProt

complete

involved_in

GO:0009089

lysine biosynthetic process via diaminopimelate

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00034

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jakobsen, OM et al. (2009) Overexpression of wild-type aspartokinase increases L-lysine production in the thermotolerant methylotrophic bacterium Bacillus methanolicus. Appl. Environ. Microbiol. 75 652-61 PubMed GONUTS page