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BACAN:ATXA

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Species (Taxon ID) Bacillus anthracis. (1392)
Gene Name(s) atxA
Protein Name(s) Anthrax toxin expression trans-acting positive regulator
External Links
UniProt Q44636
EMBL L13841
AF065404
AE011190
AE017336
AJ413928
AJ413929
PIR A48664
G59105
RefSeq NP_052815.1
NP_652902.1
YP_016477.2
PDB 4R6I
PDBsum 4R6I
ProteinModelPortal Q44636
STRING 261594.GBAA_pXO1_0146
EnsemblBacteria AAT28886
GeneID 1158705
2820309
3361723
KEGG bar:GBAA_pXO1_0146
PATRIC 24662095
eggNOG NOG09369
HOGENOM HOG000034227
OMA AIYSIQA
OrthoDB EOG65XMWP
BioCyc ANTHRA:GBAA_PXO1_0146-MONOMER
BANT261594:GJ7F-5732-MONOMER
Proteomes UP000000594
GO GO:0009405
GO:0006355
GO:0006351
Gene3D 1.10.10.10
1.10.1790.10
InterPro IPR013196
IPR007737
IPR011608
IPR011991
Pfam PF08279
PF05043
PF00874
SUPFAM SSF63520
PROSITE PS51372

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010628

positive regulation of gene expression

PMID:9234759[1]

ECO:0000315

P

Table 2. Screen for Tn917-LTV3 insertion mutants harboring CO2-enhanced atxA-dependent transcriptional lacZ fusions TABLE 3. Complementation of the atxA tcr-lacZ isolatesa

complete

GO:0010037

response to carbon dioxide

PMID:9234759[1]

ECO:0000270

P

Fig. 1b box A. Antibody to EF was not available. Boxes B, C, and D contain spots representing proteins which were CO2 and/or atxA dependent yet did not react with anti-toxin antisera. Boxes B and C show four spots which appear to be weakly atxA and CO2 dependent. Box D shows two spots which are atxA dependent but not CO2 dependent. These data indicate that synthesis of nontoxin proteins is influenced by growth in elevated CO2 and by the toxin gene regulator, AtxA.

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011608
InterPro:IPR036634

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hoffmaster, AR & Koehler, TM (1997) The anthrax toxin activator gene atxA is associated with CO2-enhanced non-toxin gene expression in Bacillus anthracis. Infect. Immun. 65 3091-9 PubMed GONUTS page