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BACAM:SUBT

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Species (Taxon ID) Bacillus amyloliquefaciens (Bacillus velezensis). (1390)
Gene Name(s) apr
Protein Name(s) Subtilisin BPN'

Alkaline protease Subtilisin DFE Subtilisin Novo

External Links
UniProt P00782
EMBL K02496
X00165
PIR B25415
RefSeq WP_013351733.1
PDB 1A2Q
1AK9
1AQN
1AU9
1DUI
1GNS
1GNV
1LW6
1S01
1S02
1SBH
1SBI
1SBN
1SBT
1SIB
1SPB
1ST2
1SUA
1SUB
1SUC
1SUD
1SUE
1SUP
1TM1
1TM3
1TM4
1TM5
1TM7
1TMG
1TO1
1TO2
1UBN
1V5I
1Y1K
1Y33
1Y34
1Y3B
1Y3C
1Y3D
1Y3F
1Y48
1Y4A
1Y4D
1YJA
1YJB
1YJC
2SBT
2SIC
2SNI
2ST1
3BGO
3CNQ
3CO0
3F49
3SIC
5SIC
PDBsum 1A2Q
1AK9
1AQN
1AU9
1DUI
1GNS
1GNV
1LW6
1S01
1S02
1SBH
1SBI
1SBN
1SBT
1SIB
1SPB
1ST2
1SUA
1SUB
1SUC
1SUD
1SUE
1SUP
1TM1
1TM3
1TM4
1TM5
1TM7
1TMG
1TO1
1TO2
1UBN
1V5I
1Y1K
1Y33
1Y34
1Y3B
1Y3C
1Y3D
1Y3F
1Y48
1Y4A
1Y4D
1YJA
1YJB
1YJC
2SBT
2SIC
2SNI
2ST1
3BGO
3CNQ
3CO0
3F49
3SIC
5SIC
ProteinModelPortal P00782
SMR P00782
IntAct P00782
MINT MINT-242921
STRING 326423.RBAM_010500
DrugBank DB03297
DB04491
DB02442
DB02325
DB01805
DB01915
MEROPS I09.001
GeneID 9780852
eggNOG COG1404
BRENDA 3.4.21.62
SABIO-RK P00782
EvolutionaryTrace P00782
PMAP-CutDB P00782
GO GO:0005576
GO:0046872
GO:0004252
GO:0042730
GO:0006508
GO:0030435
CDD cd07477
Gene3D 3.30.70.80
3.40.50.200
InterPro IPR000209
IPR023827
IPR022398
IPR023828
IPR015500
IPR009020
IPR010259
IPR034202
Pfam PF05922
PF00082
PRINTS PR00723
SUPFAM SSF52743
SSF54897
PROSITE PS00136
PS00137
PS00138

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000045

proteolysis

PMID:28382029[1]

ECO:0000315

P

Proposed model of Ba-induced autophagy and its function in eliminating E. coli. Ba upregulates the expression of Beclin1. Beclin1 promotes formation of the phagophore. The phagophore incorporates the Atg5-Atg12-Atg16 complex into its membrane to generate an autophagosome which consumes and lyses invading pathogens. AKT/MTOR is independent in this process.

complete
CACAO 12580

involved_in

GO:0042730

fibrinolysis

PMID:12524032[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

PMID:12524032[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004252

serine-type endopeptidase activity

PMID:12524032[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004252

serine-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000209
InterPro:IPR036852

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000209
InterPro:IPR036852

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

enables

GO:0008236

serine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0720

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0030435

sporulation resulting in formation of a cellular spore

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0749

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wu, Y et al. (2017) Probiotic Bacillus amyloliquefaciens SC06 Induces Autophagy to Protect against Pathogens in Macrophages. Front Microbiol 8 469 PubMed GONUTS page
  2. 2.0 2.1 2.2 Peng, Y et al. (2003) Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 134 45-52 PubMed GONUTS page