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ARATH:SDN1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) SDN1
Protein Name(s) Small RNA degrading nuclease 1
External Links
UniProt A3KPE8
EMBL AL132978
CP002686
BT030315
PIR T45863
RefSeq NP_190579.2
UniGene At.35533
ProteinModelPortal A3KPE8
SMR A3KPE8
STRING 3702.AT3G50100.1
iPTMnet A3KPE8
PaxDb A3KPE8
PRIDE A3KPE8
EnsemblPlants AT3G50100.1
GeneID 824172
Gramene AT3G50100.1
KEGG ath:AT3G50100
TAIR AT3G50100
eggNOG KOG2248
COG0847
HOGENOM HOG000083886
InParanoid A3KPE8
KO K14570
OMA CKSILGY
PhylomeDB A3KPE8
PRO PR:A3KPE8
Proteomes UP000006548
ExpressionAtlas A3KPE8
GO GO:0005634
GO:0008408
GO:0003676
GO:0000166
GO:0010587
GO:0090305
Gene3D 3.30.420.10
3.30.70.330
InterPro IPR013520
IPR012677
IPR012337
Pfam PF00929
SMART SM00479
SUPFAM SSF53098
SSF54928

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000175

3'-5'-exoribonuclease activity

PMID:18787168[1]

ECO:0000314

F

Figures 1 and 2 show that SDN1 has exoribonuclease activity and its substrates are single stranded miRNAs in arabidopsis.

complete
CACAO 12209

enables

GO:0044748

3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing

PMID:30181559[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0035198

miRNA binding

PMID:30181559[2]

ECO:0000353

physical interaction evidence used in manual assertion

AGI_LocusCode:AT1G48410

F

Seeded From UniProt

complete

involved_in

GO:0010587

miRNA catabolic process

PMID:18787168[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

PMID:18787168[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0044747

mature miRNA 3'-end processing

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0044748

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008408

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004527

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR035979
InterPro:IPR036397

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004527

exonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0269

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Ramachandran, V & Chen, X (2008) Degradation of microRNAs by a family of exoribonucleases in Arabidopsis. Science 321 1490-2 PubMed GONUTS page
  2. 2.0 2.1 Chen, J et al. (2018) Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun 9 3585 PubMed GONUTS page