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ARATH:CNX2

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) CNX2
Protein Name(s) Cyclic pyranopterin monophosphate synthase, mitochondrial

Molybdenum cofactor biosynthesis enzyme CNX2 Molybdopterin biosynthesis protein CNX2 Molybdopterin precursor Z synthase

External Links
UniProt Q39055
EMBL Z48047
AC006223
AC006533
CP002685
CP002685
CP002685
AY065265
AY096557
AY087242
PIR B84727
RefSeq NP_001031461.1
NP_001189652.1
NP_850177.2
UniGene At.19645
ProteinModelPortal Q39055
SMR Q39055
BioGrid 3101
IntAct Q39055
STRING 3702.AT2G31955.2-P
PaxDb Q39055
PRIDE Q39055
EnsemblPlants AT2G31955.1
AT2G31955.2
GeneID 817754
KEGG ath:AT2G31955
TAIR AT2G31955
eggNOG COG2896
HOGENOM HOG000228680
InParanoid Q39055
KO K03639
OMA GWIHQIR
PhylomeDB Q39055
BioCyc ARA:AT2G31955-MONOMER
ARA:GQT-879-MONOMER
ARA:GQT-880-MONOMER
MetaCyc:AT2G31955-MONOMER
Reactome REACT_187830
UniPathway UPA00344
PRO PR:Q39055
Proteomes UP000006548
Genevestigator Q39055
GO GO:0009507
GO:0005759
GO:0005739
GO:0019008
GO:0051539
GO:0061597
GO:0005525
GO:0046872
GO:0006777
Gene3D 3.20.20.70
HAMAP MF_01225_B
InterPro IPR013785
IPR006638
IPR013483
IPR000385
IPR010505
IPR007197
Pfam PF06463
PF04055
SMART SM00729
TIGRFAMs TIGR02666
PROSITE PS01305

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005739

mitochondrion

PMID:23630326[1]

ECO:0000314

C

Figure 4a.

complete
CACAO 8343

part_of

GO:0005739

mitochondrion

PMID:23630326[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009507

chloroplast

PMID:7890743[2]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

involved_in

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

PMID:29247140[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:7890743[2]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000385
InterPro:IPR006638
InterPro:IPR007197
InterPro:IPR013785

F

Seeded From UniProt

complete

involved_in

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010505
InterPro:IPR013483

P

Seeded From UniProt

complete

part_of

GO:0019008

molybdopterin synthase complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010505

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000385
InterPro:IPR013483

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006638
InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000385
InterPro:IPR010505

F

Seeded From UniProt

complete

enables

GO:0061798

GTP 3',8'-cyclase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.1.99.22

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

involved_in

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0501

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0170

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Kaufholdt, D et al. (2013) Visualization and quantification of protein interactions in the biosynthetic pathway of molybdenum cofactor in Arabidopsis thaliana. J. Exp. Bot. 64 2005-16 PubMed GONUTS page
  2. 2.0 2.1 Hoff, T et al. (1995) Isolation of two Arabidopsis cDNAs involved in early steps of molybdenum cofactor biosynthesis by functional complementation of Escherichia coli mutants. J. Biol. Chem. 270 6100-7 PubMed GONUTS page
  3. Kruse, I et al. (2018) Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria. Biochem. J. 475 495-509 PubMed GONUTS page