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ABRPR:ABRA

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Species (Taxon ID) Abrus precatorius (Indian licorice) (Glycine abrus). (3816)
Gene Name(s) No Information Provided.
Protein Name(s) Abrin-a

Abrin-a A chain rRNA N-glycosidase Linker peptide Abrin-a B chain

External Links
UniProt P11140
EMBL M98344
X54872
PIR S32429
PDB 1ABR
PDBsum 1ABR
ProteinModelPortal P11140
SMR P11140
MINT MINT-195443
PRIDE P11140
EvolutionaryTrace P11140
GO GO:0005534
GO:0030598
GO:0006952
GO:0008152
GO:0017148
GO:0045807
Gene3D 3.40.420.10
4.10.470.10
InterPro IPR001574
IPR017988
IPR016138
IPR016139
IPR017989
IPR000772
Pfam PF00652
PF00161
PRINTS PR00396
SMART SM00458
SUPFAM SSF50370
SSF56371
PROSITE PS50231
PS00275

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0031640

killing of cells of other organism

PMID:22228764[1]

ECO:0000314

P

Figure 1B and Table 1.

complete
CACAO 4121

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001574
InterPro:IPR016138
InterPro:IPR017988
InterPro:IPR036041

P

Seeded From UniProt

complete

enables

GO:0030598

rRNA N-glycosylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001574
InterPro:IPR016138
InterPro:IPR017988
InterPro:IPR017989
InterPro:IPR036041

F

Seeded From UniProt

complete

enables

GO:0030598

rRNA N-glycosylase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.2.22

F

Seeded From UniProt

complete

involved_in

GO:0045807

positive regulation of endocytosis

PMID:2016300[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030598

rRNA N-glycosylase activity

PMID:2016300[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

PMID:2016300[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005534

galactose binding

PMID:2016300[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0611

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0652

P

Seeded From UniProt

complete

enables

GO:0030246

carbohydrate binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0430

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pasetto, M et al. (2012) Reductive activation of type 2 ribosome-inactivating proteins is promoted by transmembrane thioredoxin-related protein. J. Biol. Chem. 287 7367-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Evensen, G et al. (1991) Direct molecular cloning and expression of two distinct abrin A-chains. J. Biol. Chem. 266 6848-52 PubMed GONUTS page