GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
9RHAB:Q85422
Contents
Species (Taxon ID) | Rabies virus. (11292) | |
Gene Name(s) | g protein (ECO:0000313 with EMBL:AAA63505.1) | |
Protein Name(s) | Rabies glycoprotein (ECO:0000313 with EMBL:AAA63505.1) | |
External Links | ||
UniProt | Q85422 | |
EMBL | L40426 | |
PIR | PQ0370 | |
ProteinModelPortal | Q85422 | |
GO | GO:0019031 | |
InterPro | IPR001903 | |
Pfam | PF00974 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0019031 |
viral envelope |
ECO:0000315 |
C |
Figure 1B and 1C show how the g protein of the rabies virus is required for infecting cells via binding to neuronal receptors and for viral entry. When the g protein was knocked out of the RV vector, rHEP5.0-delta G, the number of infected cells failed to increase whereas the propagation-competent RV vector rHEP5.0-CVSG was unhindered by infecting cells because it had a functional g protein. |
complete | |||||
part_of |
GO:0019031 |
viral envelope |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0019031 |
viral envelope |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ohara, S et al. (2013) Rabies virus vector transgene expression level and cytotoxicity improvement induced by deletion of glycoprotein gene. PLoS ONE 8 e80245 PubMed GONUTS page