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PMID:11448787

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Citation

Tin Su, T (2001) Cell cycle: how, when and why cells get rid of cyclin A. Curr. Biol. 11:R467-9

Abstract

Sequences outside the 'destruction box' direct the degradation of cyclin A to completion before the metaphase-anaphase transition; cyclin A that escapes timely degradation can block the metaphase-anaphase transition, impede anaphase and telophase, and impair a cell's ability to arrest in G1 of the next cell cycle.

Links

PubMed

Keywords

Amino Acid Motifs; Animals; Cell Cycle/physiology; Cyclin A/metabolism; Humans; Models, Biological; Spindle Apparatus/metabolism; Time Factors

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