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BRUA2:Q2YLT8

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0044164

host cell cytosol

PMID:23950720

ECO:0000314

C

Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspF expressing hemagglutinin displayed a cytosol localization

complete
CACAO 10979

public

GO:0020002

host cell plasma membrane

PMID:23950720

ECO:0000314

C

Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspF expressing hemagglutinin displayed a host plasma membrane localization.

complete
CACAO 10980

public

GO:0052208

modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction

PMID:23950720

ECO:0000314

P

Figure 1. TEM1 b-lactamase protein translocation reporter assay. Shows translocation of effector protein BspF (BAB1_1948)

Figure 2. VirB-dependent translocation of Brucella BsP effectors into J774.A1 cells. Shows effector protein BspF (BAB1_01948) translocated by T4SS.

Figure 4. A subset of Bsp effectors target the host secretory pathway. Shows that effector protein BspF (BAB1_1948) targets secretory pathway by colocalization with calnexin a marker of ER.

Figure 5. Ectopic expression of BspF (BAB1_1948) in HeLa cells interferes with the host secretory pathway.

Figure 7. Contribution of BspF (BAB1_1948) to inhibition of host cell secretion during infection.

complete
CACAO 11000




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