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HUMAN:BIG1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

involved_in

GO:2000114

regulation of establishment of cell polarity

PMID:22084092

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0090303

positive regulation of wound healing

PMID:22084092

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0090284

positive regulation of protein glycosylation in Golgi

PMID:17227842

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:22084092

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0034260

negative regulation of GTPase activity

PMID:15644318

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0034237

protein kinase A regulatory subunit binding

PMID:12571360

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0030837

negative regulation of actin filament polymerization

PMID:22084092

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0030532

small nuclear ribonucleoprotein complex

PMID:18292223

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0017022

myosin binding

PMID:15644318

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q13459

F

Seeded From UniProt

complete

protected

enables

GO:0017022

myosin binding

PMID:15644318

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:B2RTY4

F

Seeded From UniProt

complete

protected

involved_in

GO:0010256

endomembrane system organization

PMID:20360857

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

NOT|enables

GO:0005096

GTPase activator activity

PMID:15644318

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0007030

Golgi organization

PMID:20360857

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007030

Golgi organization

PMID:17227842

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

PMID:10716990

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005802

trans-Golgi network

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:D4A631

C

Seeded From UniProt

complete

protected

part_of

GO:0005730

nucleolus

PMID:14973189

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0005085

guanyl-nucleotide exchange factor activity

PMID:15644318

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0000139

Golgi membrane

PMID:10716990

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0016192

vesicle-mediated transport

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000070561
TAIR:locus:2025502
TAIR:locus:2084706

P

Seeded From UniProt

complete

protected

part_of

GO:0005802

trans-Golgi network

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028538
PANTHER:PTN000070561
RGD:1560793
RGD:631430
SGD:S000002577
TAIR:locus:2084706

C

Seeded From UniProt

complete

protected

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028538
PANTHER:PTN000070561
SGD:S000002577
UniProtKB:Q9Y6D5

F

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005794

Golgi apparatus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0043547

positive regulation of GTPase activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005096

P

Seeded From UniProt

complete

protected

involved_in

GO:0051897

positive regulation of protein kinase B signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:D4A631
ensembl:ENSRNOP00000007766

P

Seeded From UniProt

complete

protected

involved_in

GO:0031175

neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:D4A631
ensembl:ENSRNOP00000007766

P

Seeded From UniProt

complete

protected

part_of

GO:0005802

trans-Golgi network

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:D4A631
ensembl:ENSRNOP00000007766

C

Seeded From UniProt

complete

protected

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000904
InterPro:IPR035999

F

Seeded From UniProt

complete

protected

involved_in

GO:0032012

regulation of ARF protein signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000904
InterPro:IPR035999

P

Seeded From UniProt

complete

protected

involved_in

GO:0006887

exocytosis

PMID:10212200

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

enables

GO:0005085

guanyl-nucleotide exchange factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0344

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333
UniProtKB-SubCell:SL-0132

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

protected

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0198

C

Seeded From UniProt

complete

protected

part_of

GO:0016363

nuclear matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0181

C

Seeded From UniProt

complete

protected

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete




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