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Dai, X, Jiang, W, Zhang, Q, Xu, L, Geng, P, Zhuang, S, Petrich, BG, Jiang, C, Peng, L, Bhattacharya, S, Evans, SM, Sun, Y, Chen, J and Liang, X (2013) Requirement for Integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 11:107


Neural crest defects lead to congenital heart disease involving outflow tract malformation. Integrin-linked-Kinase (ILK) plays important roles in multiple cellular processes and embryogenesis. ILK is expressed in neural crest, but its role in neural crest and outflow tract morphogenesis remains unknown.


PubMed Online version:10.1186/1741-7007-11-107