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MOUSE:COF1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0030836

positive regulation of actin filament depolymerization

PMID:23921380

ECO:0000314

P

Figure 7 B-C show that when exposed to cofilin, the rate of actin filament depolymerization increases.

complete
CACAO 8816

protected

part_of

GO:0005615

extracellular space

PMID:24006456

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

produced_by:(CL:0002548)

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P10668

F

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

PMID:11809832

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0030042

actin filament depolymerization

PMID:11809832

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0030043

actin filament fragmentation

PMID:11809832

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0030836

positive regulation of actin filament depolymerization

PMID:23921380

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0061001

regulation of dendritic spine morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P23528

P

occurs_in:(CL:0002608)

Seeded From UniProt

complete

protected

part_of

GO:0030027

lamellipodium

PMID:25107909

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0005102

signaling receptor binding

PMID:24052308

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P97484

F

occurs_in:(UBERON:0001890)

Seeded From UniProt

complete

protected

involved_in

GO:0022604

regulation of cell morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

involved_in

GO:0007010

cytoskeleton organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:2000814

positive regulation of barbed-end actin filament capping

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:2000784

positive regulation of establishment of cell polarity regulating cell shape

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:2000147

positive regulation of cell motility

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:2000146

negative regulation of cell motility

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1990314

cellular response to insulin-like growth factor stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1905875

negative regulation of postsynaptic density organization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1905873

positive regulation of protein localization to cell leading edge

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1904783

positive regulation of NMDA glutamate receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1902951

negative regulation of dendritic spine maintenance

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

enables

GO:1902936

phosphatidylinositol bisphosphate binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

F

Seeded From UniProt

complete

protected

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0098885

modification of postsynaptic actin cytoskeleton

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

part_of

GO:0097060

synaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

part_of

GO:0090732

cofilin-actin rod

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071364

cellular response to epidermal growth factor stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071356

cellular response to tumor necrosis factor

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071354

cellular response to interleukin-6

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071347

cellular response to interleukin-1

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0061001

regulation of dendritic spine morphogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0060999

positive regulation of dendritic spine development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051894

positive regulation of focal adhesion assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051511

negative regulation of unidimensional cell growth

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

F

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045862

positive regulation of proteolysis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045792

negative regulation of cell size

PMID:16286931

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P45592

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0044794

positive regulation by host of viral process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043200

response to amino acid

PMID:17018287

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0043197

dendritic spine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0032232

negative regulation of actin filament bundle assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

part_of

GO:0031966

mitochondrial membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0031915

positive regulation of synaptic plasticity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

part_of

GO:0031252

cell leading edge

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

part_of

GO:0030864

cortical actin cytoskeleton

PMID:15548599

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0030864

cortical actin cytoskeleton

PMID:15004221

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030836

positive regulation of actin filament depolymerization

PMID:15548599

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030835

negative regulation of actin filament depolymerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

part_of

GO:0030426

growth cone

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030307

positive regulation of cell growth

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

part_of

GO:0030175

filopodium

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030042

actin filament depolymerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030030

cell projection organization

PMID:16286931

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P45592

P

Seeded From UniProt

complete

protected

part_of

GO:0030027

lamellipodium

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030010

establishment of cell polarity

PMID:15606898

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3574399

P

occurs_in:(CL:0000333)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0022604

regulation of cell morphogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

enables

GO:0019903

protein phosphatase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010593

negative regulation of lamellipodium assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010592

positive regulation of lamellipodium assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007162

negative regulation of cell adhesion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007015

actin filament organization

PMID:15606898

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3574399

P

occurs_in:(CL:0000333)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007010

cytoskeleton organization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006606

protein import into nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006468

protein phosphorylation

PMID:17018287

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005925

focal adhesion

PMID:29162887

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

C

Seeded From UniProt

complete

protected

part_of

GO:0005911

cell-cell junction

PMID:23793062

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:15548599

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23528

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

C

Seeded From UniProt

complete

protected

enables

GO:0003779

actin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69285

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001842

neural fold formation

PMID:15649475

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3574399

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001755

neural crest cell migration

PMID:15649475

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3574399

P

  • occurs_in:(EMAPA:16039)
  • results_in_movement_of:(CL:0000333)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0000281

mitotic cytokinesis

PMID:15548599

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0061001

regulation of dendritic spine morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

F

Seeded From UniProt

complete

protected

involved_in

GO:0044794

positive regulation by host of viral process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

involved_in

GO:0030042

actin filament depolymerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

involved_in

GO:0022604

regulation of cell morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

involved_in

GO:0009615

response to virus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

involved_in

GO:0007010

cytoskeleton organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

P

Seeded From UniProt

complete

protected

part_of

GO:0005925

focal adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23528
ensembl:ENSP00000432660

C

Seeded From UniProt

complete

protected

involved_in

GO:2000814

positive regulation of barbed-end actin filament capping

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:2000784

positive regulation of establishment of cell polarity regulating cell shape

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:2000147

positive regulation of cell motility

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:2000146

negative regulation of cell motility

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:1990314

cellular response to insulin-like growth factor stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:1905875

negative regulation of postsynaptic density organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:1905873

positive regulation of protein localization to cell leading edge

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:1904783

positive regulation of NMDA glutamate receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:1902951

negative regulation of dendritic spine maintenance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

enables

GO:1902936

phosphatidylinositol bisphosphate binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

F

Seeded From UniProt

complete

protected

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0098885

modification of postsynaptic actin cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0097060

synaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

part_of

GO:0090732

cofilin-actin rod

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0071364

cellular response to epidermal growth factor stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0071362

cellular response to ether

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0071356

cellular response to tumor necrosis factor

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0071354

cellular response to interleukin-6

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0071347

cellular response to interleukin-1

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0060999

positive regulation of dendritic spine development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0051894

positive regulation of focal adhesion assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0051511

negative regulation of unidimensional cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

F

Seeded From UniProt

complete

protected

involved_in

GO:0045862

positive regulation of proteolysis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0045792

negative regulation of cell size

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0043197

dendritic spine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

part_of

GO:0043025

neuronal cell body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0032232

negative regulation of actin filament bundle assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0031966

mitochondrial membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0031915

positive regulation of synaptic plasticity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0031252

cell leading edge

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0030835

negative regulation of actin filament depolymerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0030426

growth cone

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0030307

positive regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0030175

filopodium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0030030

cell projection organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0030027

lamellipodium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

involved_in

GO:0021766

hippocampus development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

enables

GO:0019903

protein phosphatase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

F

Seeded From UniProt

complete

protected

involved_in

GO:0014823

response to activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0014070

response to organic cyclic compound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0010593

negative regulation of lamellipodium assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0010592

positive regulation of lamellipodium assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0007162

negative regulation of cell adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

involved_in

GO:0006606

protein import into nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

C

Seeded From UniProt

complete

protected

enables

GO:0003779

actin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P45592
ensembl:ENSRNOP00000059624

F

Seeded From UniProt

complete

protected

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002108

F

Seeded From UniProt

complete

protected

part_of

GO:0015629

actin cytoskeleton

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017904
InterPro:IPR027234

C

Seeded From UniProt

complete

protected

involved_in

GO:0030042

actin filament depolymerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017904
InterPro:IPR027234

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-NUL-421139
Reactome:R-MMU-482767

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

protected

part_of

GO:0005576

extracellular region

Reactome:R-MMU-482767

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

protected

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

protected

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

part_of

GO:0031258

lamellipodium membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0292

C

Seeded From UniProt

complete

protected

part_of

GO:0032587

ruffle membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0301

C

Seeded From UniProt

complete

protected

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

protected

part_of

GO:0016363

nuclear matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0181

C

Seeded From UniProt

complete




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