GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

TableEdit

Jump to: navigation, search

HUMAN:WASP

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0002625

regulation of T cell antigen processing and presentation

PMID:22804504

ECO:0000315

P

Fig 7b shows that the stained WASP-deficient T-cells show a reduction in the presence of antigens just on the mid body. Instead they are spread all the way down to the uropod.

complete
CACAO 5733

public

GO:2000146

negative regulation of cell motility

PMID:22804504

ECO:0000315

P

Fig 2a shows that in the presence of JY cells, the motility of WASP deficient T-cells is significantly increased.

complete
CACAO 5734

protected

NOT|involved_in

GO:2001032

regulation of double-strand break repair via nonhomologous end joining

PMID:29925947

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0035861

site of double-strand break

PMID:29925947

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0030041

actin filament polymerization

PMID:29925947

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:1905168

positive regulation of double-strand break repair via homologous recombination

PMID:29925947

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:29925947

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:20574068

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:20574068

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0031267

small GTPase binding

PMID:10724160

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P60953

F

Seeded From UniProt

complete

protected

involved_in

GO:0008064

regulation of actin polymerization or depolymerization

PMID:8625410

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

NOT|involved_in

GO:0007266

Rho protein signal transduction

PMID:8625410

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0048365

Rac GTPase binding

PMID:8625410

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P63000

F

Seeded From UniProt

complete

protected

involved_in

GO:0032488

Cdc42 protein signal transduction

PMID:8625410

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:19798448

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9XUS7

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:19798448

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q5T0N5

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:19798448

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q19253

F

Seeded From UniProt

complete

protected

involved_in

GO:0051492

regulation of stress fiber assembly

PMID:8625410

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P63000

P

Seeded From UniProt

complete

protected

involved_in

GO:0010591

regulation of lamellipodium assembly

PMID:8625410

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P63000

P

Seeded From UniProt

complete

protected

involved_in

GO:0051492

regulation of stress fiber assembly

PMID:8625410

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

protected

involved_in

GO:0010591

regulation of lamellipodium assembly

PMID:8625410

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

protected

part_of

GO:0005884

actin filament

PMID:8625410

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0051497

negative regulation of stress fiber assembly

PMID:8625410

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0031267

small GTPase binding

PMID:8625410

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P60953

F

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

PMID:8625410

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000775)

Seeded From UniProt

complete

protected

involved_in

GO:2000146

negative regulation of cell motility

PMID:22804504

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0002625

regulation of T cell antigen processing and presentation

PMID:22804504

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q06187

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q06187

F

Seeded From UniProt

complete

protected

enables

GO:0043274

phospholipase binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P19174

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P19174

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P62993

F

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42680

F

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q08881

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q08881

F

Seeded From UniProt

complete

protected

enables

GO:0017124

SH3 domain binding

PMID:8892607

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42680

F

Seeded From UniProt

complete

protected

part_of

GO:0070062

extracellular exosome

PMID:20458337

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000639)

Seeded From UniProt

complete

protected

involved_in

GO:0006955

immune response

PMID:8069912

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0051666

actin cortical patch localization

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001506182
SGD:S000004329
SGD:S000005707

P

Seeded From UniProt

complete

protected

involved_in

GO:0051127

positive regulation of actin nucleation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001506182
PomBase:SPBC13E7.09

P

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0243516
PANTHER:PTN001506182

F

Seeded From UniProt

complete

protected

part_of

GO:0030479

actin cortical patch

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001506182
PomBase:SPAC4F10.15c
PomBase:SPBC13E7.09
SGD:S000004329
SGD:S000005707
UniProtKB:A0A1D8PU03

C

Seeded From UniProt

complete

protected

involved_in

GO:0030048

actin filament-based movement

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105059
MGI:MGI:2178801
PANTHER:PTN001506182

P

Seeded From UniProt

complete

protected

involved_in

GO:0006897

endocytosis

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001506182
PomBase:SPAC4F10.15c
SGD:S000004329
UniProtKB:A0A1D8PU03

P

Seeded From UniProt

complete

protected

part_of

GO:0005884

actin filament

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2178801
PANTHER:PTN001506182
RGD:620887
UniProtKB:P42768

C

Seeded From UniProt

complete

protected

involved_in

GO:0000147

actin cortical patch assembly

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001506182
PomBase:SPAC4F10.15c
PomBase:SPBC13E7.09

P

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

PMID:18650809

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42768

F

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

PMID:12769847

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42768

F

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

PMID:10724160

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42768

F

Seeded From UniProt

complete

protected

involved_in

GO:0050790

regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0030695

P

Seeded From UniProt

complete

protected

involved_in

GO:0071346

cellular response to interferon-gamma

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

part_of

GO:0045335

phagocytic vesicle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

C

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

F

Seeded From UniProt

complete

protected

involved_in

GO:0042110

T cell activation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

involved_in

GO:0030048

actin filament-based movement

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

involved_in

GO:0030041

actin filament polymerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

involved_in

GO:0016197

endosomal transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

part_of

GO:0012506

vesicle membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

C

Seeded From UniProt

complete

protected

involved_in

GO:0008154

actin polymerization or depolymerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

P

Seeded From UniProt

complete

protected

part_of

GO:0005911

cell-cell junction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70315
ensembl:ENSMUSP00000033505

C

Seeded From UniProt

complete

protected

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003124
InterPro:IPR027641

F

Seeded From UniProt

complete

protected

involved_in

GO:0007015

actin filament organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011026
InterPro:IPR027641

P

Seeded From UniProt

complete

protected

involved_in

GO:2000601

positive regulation of Arp2/3 complex-mediated actin nucleation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027641

P

Seeded From UniProt

complete

protected

part_of

GO:0015629

actin cytoskeleton

PMID:8625410

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0008544

epidermis development

PMID:8069912

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0008154

actin polymerization or depolymerization

PMID:8625410

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007596

blood coagulation

PMID:8069912

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006952

defense response

PMID:8069912

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0065003

protein-containing complex assembly

PMID:8625410

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0030695

GTPase regulator activity

PMID:8625410

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0050852

T cell receptor signaling pathway

Reactome:R-HSA-202403

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0038096

Fc-gamma receptor signaling pathway involved in phagocytosis

Reactome:R-HSA-2029480

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-HSA-430180
Reactome:R-HSA-2197698
Reactome:R-HSA-2197691
Reactome:R-HSA-2197690
Reactome:R-HSA-2029466

ECO:0000304

author statement supported by traceable reference used in manual assertion





C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete




Cancel