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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0004517

nitric-oxide synthase activity

PMID:1689048

ECO:0000314

F

figure 3

complete
CACAO 4515

protected

involved_in

GO:0033138

positive regulation of peptidyl-serine phosphorylation

PMID:28089352

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • has_input:(UniProtKB:P10636)
  • occurs_in:(CL:0000540)

Seeded From UniProt

complete

protected

part_of

GO:0042383

sarcolemma

PMID:27225184

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002129)

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

PMID:1689048

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

C

Seeded From UniProt

complete

protected

part_of

GO:0045202

synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

C

Seeded From UniProt

complete

protected

part_of

GO:0045121

membrane raft

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

C

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

C

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

F

Seeded From UniProt

complete

protected

involved_in

GO:0071363

cellular response to growth factor stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0051926

negative regulation of calcium ion transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0051612

negative regulation of serotonin uptake

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0051346

negative regulation of hydrolase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0043267

negative regulation of potassium ion transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0042738

exogenous drug catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0035066

positive regulation of histone acetylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0018119

peptidyl-cysteine S-nitrosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0006941

striated muscle contraction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0002028

regulation of sodium ion transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0098735

positive regulation of the force of heart contraction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:1902307

positive regulation of sodium ion transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

P

Seeded From UniProt

complete

protected

enables

GO:0097110

scaffold protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

enables

GO:0050661

NADP binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:17027776

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

C

Seeded From UniProt

complete

protected

enables

GO:0046870

cadmium ion binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

involved_in

GO:0042311

vasodilation

PMID:18391107

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0042311

vasodilation

PMID:18048451

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0044325

ion channel binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

part_of

GO:0032991

protein-containing complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

C

Seeded From UniProt

complete

protected

part_of

GO:0042383

sarcolemma

PMID:7545544

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0034617

tetrahydrobiopterin binding

PMID:7488039

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0033555

multicellular organismal response to stress

PMID:18391107

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0020037

heme binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

involved_in

GO:0018119

peptidyl-cysteine S-nitrosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

P

Seeded From UniProt

complete

protected

enables

GO:0017080

sodium channel regulator activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

part_of

GO:0016529

sarcoplasmic reticulum

PMID:9892689

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0010181

FMN binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

involved_in

GO:0009408

response to heat

PMID:18048451

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006809

nitric oxide biosynthetic process

PMID:7545544

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

P

Seeded From UniProt

complete

protected

involved_in

GO:0006527

arginine catabolic process

PMID:7545544

ECO:0000305

curator inference used in manual assertion

GO:0004517

P

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

PMID:7545544

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

C

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

PMID:7545544

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z0J4

F

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

F

Seeded From UniProt

complete

protected

part_of

GO:0001917

photoreceptor inner segment

PMID:17027776

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P29476

C

Seeded From UniProt

complete

protected

involved_in

GO:0001666

response to hypoxia

PMID:16276418

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0098924

retrograde trans-synaptic signaling by nitric oxide

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97360
PANTHER:PTN000454042

P

Seeded From UniProt

complete

protected

enables

GO:0050660

flavin adenine dinucleotide binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10191
MGI:MGI:97361
PANTHER:PTN000453956
RGD:3184
RGD:68335
UniProtKB:O08336
UniProtKB:O08394
UniProtKB:Q9UBK8
UniProtKB:Q9UHB4

F

Seeded From UniProt

complete

protected

involved_in

GO:0045776

negative regulation of blood pressure

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000453988
RGD:3184

P

Seeded From UniProt

complete

protected

involved_in

GO:0032496

response to lipopolysaccharide

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97361
PANTHER:PTN001066032
RGD:3184
RGD:3185
RGD:3186
ZFIN:ZDB-GENE-040305-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0031284

positive regulation of guanylate cyclase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001066032
UniProtKB:P29473
UniProtKB:P29474

P

Seeded From UniProt

complete

protected

enables

GO:0016491

oxidoreductase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97744
PANTHER:PTN000453956
UniProtKB:Q9UHB4

F

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000454042
RGD:3184

C

Seeded From UniProt

complete

protected

part_of

GO:0012506

vesicle membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001066032
RGD:3184
RGD:3185
RGD:3186

C

Seeded From UniProt

complete

protected

enables

GO:0010181

FMN binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10191
MGI:MGI:97361
PANTHER:PTN000453956
RGD:3184
RGD:68335
UniProtKB:O08336
UniProtKB:O08394
UniProtKB:Q9UBK8
UniProtKB:Q9UHB4

F

Seeded From UniProt

complete

protected

involved_in

GO:0009725

response to hormone

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002322100
RGD:3185

P

Seeded From UniProt

complete

protected

involved_in

GO:0007263

nitric oxide mediated signal transduction

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001066032
RGD:3184
ZFIN:ZDB-GENE-001101-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0006809

nitric oxide biosynthetic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97360
MGI:MGI:97361
MGI:MGI:97362
PANTHER:PTN001066032
RGD:3184
RGD:3185
RGD:3186
UniProtKB:P29473
UniProtKB:P29474
UniProtKB:P35228

P

Seeded From UniProt

complete

protected

involved_in

GO:0006527

arginine catabolic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97361
PANTHER:PTN001066032
RGD:3184
UniProtKB:P29473
UniProtKB:P29474
UniProtKB:P35228

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001066032
RGD:3184
RGD:3186
UniProtKB:P29475

C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000453956
RGD:3184
RGD:3185
RGD:3186
UniProtKB:P35228
UniProtKB:Q9SB48
UniProtKB:Q9UHB4

C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000453765
RGD:3184
RGD:3185
RGD:3186
UniProtKB:P35228

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97362
PANTHER:PTN001066032
RGD:3184
RGD:3185
RGD:3186

C

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0011676
MGI:MGI:97360
MGI:MGI:97361
MGI:MGI:97362
PANTHER:PTN001066032
RGD:3184
RGD:3185
RGD:3186
UniProtKB:P29473
UniProtKB:P29474
UniProtKB:P29475
UniProtKB:P35228

F

Seeded From UniProt

complete

protected

enables

GO:0003958

NADPH-hemoprotein reductase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000453763
PomBase:SPBC29A10.01
RGD:68335
SGD:S000001084
TAIR:locus:2128951
UniProtKB:A0A1D8PLR7
UniProtKB:O08336
UniProtKB:O08394
UniProtKB:P16435
UniProtKB:Q9UBK8

F

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0140196

positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0099163

synaptic signaling by nitric oxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0098924

retrograde trans-synaptic signaling by nitric oxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0098735

positive regulation of the force of heart contraction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0071363

cellular response to growth factor stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0051926

negative regulation of calcium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0051612

negative regulation of serotonin uptake

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0051346

negative regulation of hydrolase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0050767

regulation of neurogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0045121

membrane raft

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0044305

calyx of Held

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

involved_in

GO:0043267

negative regulation of potassium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0042738

exogenous drug catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

part_of

GO:0042383

sarcolemma

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

involved_in

GO:0035066

positive regulation of histone acetylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

part_of

GO:0033017

sarcoplasmic reticulum membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0030315

T-tubule

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0030018

Z disc

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

involved_in

GO:0018119

peptidyl-cysteine S-nitrosylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0006941

striated muscle contraction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

involved_in

GO:0006809

nitric oxide biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

C

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

F

Seeded From UniProt

complete

protected

involved_in

GO:0002028

regulation of sodium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Z0J4
ensembl:ENSMUSP00000120421

P

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004030
InterPro:IPR012144
InterPro:IPR036119

F

Seeded From UniProt

complete

protected

enables

GO:0005516

calmodulin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012144

F

Seeded From UniProt

complete

protected

involved_in

GO:0006809

nitric oxide biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004030
InterPro:IPR012144
InterPro:IPR036119

P

Seeded From UniProt

complete

protected

enables

GO:0010181

FMN binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR008254
InterPro:IPR012144

F

Seeded From UniProt

complete

protected

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR017927
InterPro:IPR023173

F

Seeded From UniProt

complete

protected

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012144

F

Seeded From UniProt

complete

protected

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012144

F

Seeded From UniProt

complete

protected

enables

GO:0050661

NADP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012144

F

Seeded From UniProt

complete

protected

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR004030
InterPro:IPR017927
InterPro:IPR023173
InterPro:IPR036119

P

Seeded From UniProt

complete

protected

enables

GO:0004517

nitric-oxide synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.13.39

F

Seeded From UniProt

complete

protected

involved_in

GO:0060314

regulation of ryanodine-sensitive calcium-release channel activity

PMID:21536106

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

  • occurs_in:(UBERON:0002349)
  • occurs_in:(GO:0016529)

Seeded From UniProt

complete

protected

enables

GO:0044325

ion channel binding

PMID:21536106

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

  • occurs_in:(UBERON:0000948)
  • has_direct_input:(UniProtKB:Q92736)
  • occurs_in:(GO:0016529)

Seeded From UniProt

complete

protected

involved_in

GO:1902514

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

PMID:21536106

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

occurs_in:(CL:0002098)

Seeded From UniProt

complete

protected

colocalizes_with

GO:1990425

ryanodine receptor complex

PMID:21536106

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

  • part_of:(UBERON:0002349)
  • part_of:(GO:0016529)

Seeded From UniProt

complete

protected

involved_in

GO:0055117

regulation of cardiac muscle contraction

PMID:9892689

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0042136

neurotransmitter biosynthetic process

PMID:7545544

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0034618

arginine binding

PMID:17029414

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0010523

negative regulation of calcium ion transport into cytosol

PMID:17568574

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007520

myoblast fusion

PMID:7545544

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:17892502

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:1903779

regulation of cardiac conduction

Reactome:R-HSA-5578775

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0045454

cell redox homeostasis

Reactome:R-HSA-1222556

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-HSA-5617178
Reactome:R-HSA-418436

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

protected

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

protected

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

protected

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

protected

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

protected

part_of

GO:0043197

dendritic spine

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0284

C

Seeded From UniProt

complete

protected

part_of

GO:0042383

sarcolemma

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0238

C

Seeded From UniProt

complete




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