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HUMAN:HEM6

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

enables

GO:0042803

protein homodimerization activity

PMID:16176984

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0019353

protoporphyrinogen IX biosynthetic process from glutamate

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12189
PANTHER:PTN000079415

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000079415
SGD:S000002451
UniProtKB:P36551
UniProtKB:Q8IHU1

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12189
PANTHER:PTN000079415

C

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12189
MGI:MGI:104841
PANTHER:PTN000079415
RGD:1311817
SGD:S000002451
TAIR:locus:2825062
UniProtKB:P43898
UniProtKB:P72848
UniProtKB:Q8IHU1

F

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36552
ensembl:ENSMUSP00000055455

C

Seeded From UniProt

complete

protected

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36552
ensembl:ENSMUSP00000055455

P

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36552
ensembl:ENSMUSP00000055455

C

Seeded From UniProt

complete

protected

enables

GO:0005212

structural constituent of eye lens

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36552
ensembl:ENSMUSP00000055455

F

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36552
ensembl:ENSMUSP00000055455

F

Seeded From UniProt

complete

protected

involved_in

GO:0051597

response to methylmercury

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0046685

response to arsenic-containing substance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

F

Seeded From UniProt

complete

protected

involved_in

GO:0017085

response to insecticide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0010288

response to lead ion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0010039

response to iron ion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0010035

response to inorganic substance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

involved_in

GO:0006782

protoporphyrinogen IX biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

P

Seeded From UniProt

complete

protected

part_of

GO:0005758

mitochondrial intermembrane space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

C

Seeded From UniProt

complete

protected

part_of

GO:0005743

mitochondrial inner membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

C

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

C

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3B7D0
ensembl:ENSRNOP00000002257

F

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001260
InterPro:IPR018375
InterPro:IPR036406

F

Seeded From UniProt

complete

protected

involved_in

GO:0006779

porphyrin-containing compound biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001260
InterPro:IPR018375
InterPro:IPR036406

P

Seeded From UniProt

complete

protected

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001260
InterPro:IPR018375
InterPro:IPR036406

P

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.3.3.3

F

Seeded From UniProt

complete

protected

involved_in

GO:0006783

heme biosynthetic process

PMID:8159699
Reactome:R-HSA-189451

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

PMID:8407975

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0004109

coproporphyrinogen oxidase activity

PMID:9888388

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0005758

mitochondrial intermembrane space

Reactome:R-HSA-189421

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

protected

involved_in

GO:0006779

porphyrin-containing compound biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0627

P

Seeded From UniProt

complete

protected

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

protected

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0350

P

Seeded From UniProt

complete

protected

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

protected

part_of

GO:0005758

mitochondrial intermembrane space

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0169

C

Seeded From UniProt

complete

protected

involved_in

GO:0006782

protoporphyrinogen IX biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00251

P

Seeded From UniProt

complete




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