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MOUSE:SMN

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0015030

Cajal body

PMID:11470819

ECO:0000315

C

Mutant mice cannot "condense Sm proteins nor recruit members of the SMN protein complex. Transient expression of wild-type mouse coilin in knockout cells results in formation of CBs and restores these missing epitopes. Our data demonstrate that full-length coilin is essential for proper formation and/or maintenance of CBs and that recruitment of snRNP and SMN complex proteins to these nuclear subdomains requires sequences within the coilin COOH terminus."

complete
CACAO 3674

protected

part_of

GO:0043204

perikaryon

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q06787

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q06787

C

Seeded From UniProt

complete

protected

part_of

GO:0036464

cytoplasmic ribonucleoprotein granule

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q06787

C

Seeded From UniProt

complete

protected

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

P

Seeded From UniProt

complete

protected

part_of

GO:0097504

Gemini of coiled bodies

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0034719

SMN-Sm protein complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0032797

SMN complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0015030

Cajal body

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

involved_in

GO:0000387

spliceosomal snRNP assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16637

P

Seeded From UniProt

complete

protected

part_of

GO:0097504

Gemini of coiled bodies

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0097504

Gemini of coiled bodies

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620755

C

Seeded From UniProt

complete

protected

part_of

GO:0043204

perikaryon

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

F

Seeded From UniProt

complete

protected

part_of

GO:0036464

cytoplasmic ribonucleoprotein granule

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0034719

SMN-Sm protein complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0033120

positive regulation of RNA splicing

PMID:22037760

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0032797

SMN complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

enables

GO:0017134

fibroblast growth factor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620755

F

Seeded From UniProt

complete

protected

part_of

GO:0015030

Cajal body

PMID:24067532

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0015030

Cajal body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010975

regulation of neuron projection development

PMID:24067532

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:2179069

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007409

axonogenesis

PMID:20176735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007019

microtubule depolymerization

PMID:20176735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:11181573

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620755

C

Seeded From UniProt

complete

protected

part_of

GO:0005730

nucleolus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620755

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:11181573

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q16637

C

Seeded From UniProt

complete

protected

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010304

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010304

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010304

C

Seeded From UniProt

complete

protected

involved_in

GO:0006397

mRNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010304

P

Seeded From UniProt

complete

protected

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

protected

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

protected

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

protected

involved_in

GO:0008380

RNA splicing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0508

P

Seeded From UniProt

complete

protected

part_of

GO:0042995

cell projection

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966
UniProtKB-SubCell:SL-0280

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

part_of

GO:0097504

Gemini of coiled bodies

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0127

C

Seeded From UniProt

complete

protected

part_of

GO:0030018

Z disc

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0314

C

Seeded From UniProt

complete

protected

part_of

GO:0043204

perikaryon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0197

C

Seeded From UniProt

complete

protected

part_of

GO:0015030

Cajal body

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0031

C

Seeded From UniProt

complete




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