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DROME:Q7KTX7
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:0004842 |
ubiquitin-protein ligase activity |
PMID:17456438 |
ECO:0000314 |
F |
Figure 2 |
complete | ||||
public |
GO:0044743 |
intracellular protein transmembrane import |
PMID:20194754 |
ECO:0000316 |
UniProtKB:Q0KHV6
|
P |
Figure 2 shows PINK1 is required for Parkin translocation |
complete | |||
public |
GO:0031398 |
positive regulation of protein ubiquitination |
PMID:20194754 |
ECO:0000314 |
P |
Figure 4 shows parkin overexpression can cause mfn ubiquitination in the absense of PINK1 |
complete | ||||
public |
GO:0090141 |
positive regulation of mitochondrial fission |
PMID:20194754 |
ECO:0000316 |
UniProtKB:Q0KHV6
|
P |
Figure 1 shows Parkin and PINK1 activity promotes mitochondrial fission |
complete | |||
public |
GO:0010637 |
negative regulation of mitochondrial fusion |
PMID:20194754 |
ECO:0000316 |
UniProtKB:Q0KHV6
|
P |
Figure 1 shows Parkin and PINK1 activity inhibits mitochondrial fusion |
complete | |||
protected |
involved_in |
GO:1904457 |
positive regulation of neuronal action potential |
PMID:28435104 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:1904061 |
positive regulation of locomotor rhythm |
PMID:28435104 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
PMID:17456438 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0048078 |
positive regulation of compound eye pigmentation |
PMID:19692353 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:1900407 |
regulation of cellular response to oxidative stress |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041100 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0017418 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0042981 |
regulation of apoptotic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188399 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1355296 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0031624 |
ubiquitin conjugating enzyme binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0017418 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0010821 |
regulation of mitochondrion organization |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041100 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0017418 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005829 |
cytosol |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188399 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005794 |
Golgi apparatus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188399 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005783 |
endoplasmic reticulum |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188399 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005739 |
mitochondrion |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041100 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0017418 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0001933 |
negative regulation of protein phosphorylation |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188399 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0000422 |
autophagy of mitochondrion |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041100 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041100 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0000151 |
ubiquitin ligase complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000188395 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0000266 |
mitochondrial fission |
PMID:18230723 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0261276 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0070050 |
neuron cellular homeostasis |
PMID:17687034 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:17687034 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0008344 |
adult locomotory behavior |
PMID:17687034 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:17456438 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
PMID:17456438 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:17456438 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0031624 |
ubiquitin conjugating enzyme binding |
PMID:17456438 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
HGNC:12490 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0051865 |
protein autoubiquitination |
PMID:17456438 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:17123504 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007283 |
spermatogenesis |
PMID:17123504 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006979 |
response to oxidative stress |
PMID:15911761 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0046329 |
negative regulation of JNK cascade |
PMID:16002472 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:12642658 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:24852371 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0008344 |
adult locomotory behavior |
PMID:24852371 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
PMID:24898855 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000422 |
autophagy of mitochondrion |
PMID:24192653 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0055069 |
zinc ion homeostasis |
PMID:20302514 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007283 |
spermatogenesis |
PMID:21383066 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006979 |
response to oxidative stress |
PMID:21383066 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0048477 |
oogenesis |
PMID:21383066 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:20869429 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0048477 |
oogenesis |
PMID:20869429 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:1900407 |
regulation of cellular response to oxidative stress |
PMID:20483372 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0046329 |
negative regulation of JNK cascade |
PMID:20496123 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0010303 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0046329 |
negative regulation of JNK cascade |
PMID:20496123 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0000229 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:20194754 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
colocalizes_with |
GO:0005739 |
mitochondrion |
PMID:20194754 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0010637 |
negative regulation of mitochondrial fusion |
PMID:20194754 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0090141 |
positive regulation of mitochondrial fission |
PMID:20194754 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000422 |
autophagy of mitochondrion |
PMID:20194754 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:20194754 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0010821 |
regulation of mitochondrion organization |
PMID:19546216 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005739 |
mitochondrion |
PMID:18957282 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030382 |
sperm mitochondrion organization |
PMID:18799731 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:18799731 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:18443288 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000266 |
mitochondrial fission |
PMID:18230723 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0026479 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:18230723 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000266 |
mitochondrial fission |
PMID:18230723 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0029870 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0008345 |
larval locomotory behavior |
PMID:27430166 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006513 |
protein monoubiquitination |
PMID:29689197 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0042803 |
protein homodimerization activity |
PMID:29689197 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007005 |
mitochondrion organization |
PMID:29456190 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003977 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005739 |
mitochondrion |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003977 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005829 |
cytosol |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003977 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031127 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000038 |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000038 |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000038 |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000104 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000141802 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000104 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000141802 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0000151 |
ubiquitin ligase complex |
GO_REF:0000104 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000141802 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000041 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete |
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