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HUMAN:GLUC

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

protected

involved_in

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

protected

enables

GO:0031769

glucagon receptor binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668

F

Seeded From UniProt

complete

protected

involved_in

GO:0010737

protein kinase A signaling

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

protected

involved_in

GO:0007188

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668

P

Seeded From UniProt

complete

protected

part_of

GO:0005615

extracellular space

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008
RGD:2668

C

Seeded From UniProt

complete

protected

enables

GO:0005179

hormone activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668
UniProtKB:P01272

F

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

PMID:22212535

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P01275

F

Seeded From UniProt

complete

protected

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

protected

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

protected

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

protected

involved_in

GO:1900118

negative regulation of execution phase of apoptosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0090280

positive regulation of calcium ion import

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0051571

positive regulation of histone H3-K4 methylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0050796

regulation of insulin secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0045860

positive regulation of protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0035948

positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0033138

positive regulation of peptidyl-serine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0032092

positive regulation of protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0010737

protein kinase A signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

C

Seeded From UniProt

complete

protected

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

C

Seeded From UniProt

complete

protected

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532
InterPro:IPR015550

F

Seeded From UniProt

complete

protected

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532

C

Seeded From UniProt

complete

protected

involved_in

GO:0007631

feeding behavior

PMID:8538742

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

PMID:9990065
PMID:7929237
Reactome:R-HSA-388396

ECO:0000304

author statement supported by traceable reference used in manual assertion



P

Seeded From UniProt

complete

protected

enables

GO:0005102

signaling receptor binding

PMID:9990065

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0071377

cellular response to glucagon stimulus

Reactome:R-HSA-163359

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0050796

regulation of insulin secretion

Reactome:R-HSA-422356
Reactome:R-HSA-400508

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

protected

part_of

GO:0034774

secretory granule lumen

Reactome:R-HSA-421416
Reactome:R-HSA-383313

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

protected

part_of

GO:0005788

endoplasmic reticulum lumen

Reactome:R-HSA-421416
Reactome:R-HSA-381799

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

protected

part_of

GO:0005576

extracellular region

Reactome:R-HSA-9023633
Reactome:R-HSA-9023632
Reactome:R-HSA-825631
Reactome:R-HSA-749452
Reactome:R-HSA-749448
Reactome:R-HSA-744887
Reactome:R-HSA-744886
Reactome:R-HSA-420123
Reactome:R-HSA-383313
Reactome:R-HSA-381612
Reactome:R-HSA-379048
Reactome:R-HSA-379044
Reactome:R-HSA-163625

ECO:0000304

author statement supported by traceable reference used in manual assertion













C

Seeded From UniProt

complete

protected

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

protected

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete




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