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MOUSE:MET

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0007268

synaptic transmission

PMID:21490227

ECO:0000315

P

Figure 3F, G showed that KO Met mice had a higher synaptic strength input (amplitude) from layer 2/3 to corticostriatal neurons compared to wild type.

complete
CACAO 3273

public

GO:0060079

regulation of excitatory postsynaptic membrane potential

PMID:21490227

ECO:0000315

P

Figure 5D, shows that knockout Met mice had greater strength in unitary EPSC than wild type, by a factor of 1.4.

complete
CACAO 3274

protected

involved_in

GO:0060079

excitatory postsynaptic potential

PMID:21490227

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007268

chemical synaptic transmission

PMID:21490227

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0060079

excitatory postsynaptic potential

PMID:21490227

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0050804

modulation of chemical synaptic transmission

PMID:21490227

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:2001028

positive regulation of endothelial cell chemotaxis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

involved_in

GO:0071526

semaphorin-plexin signaling pathway

PMID:15218527

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0050918

positive chemotaxis

PMID:15218527

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0043235

receptor complex

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015380
FB:FBgn0024245
FB:FBgn0033791
PANTHER:PTN002356460
UniProtKB:A6QR62
UniProtKB:O15146
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P17948
UniProtKB:P21860
UniProtKB:P35916
UniProtKB:Q01973
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16288
UniProtKB:Q16620

C

Seeded From UniProt

complete

protected

involved_in

GO:0031016

pancreas development

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002814515
RGD:3082
ZFIN:ZDB-GENE-041014-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0030182

neuron differentiation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002814515
RGD:3082
ZFIN:ZDB-GENE-041014-1

P

Seeded From UniProt

complete

protected

enables

GO:0017147

Wnt-protein binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015380
FB:FBgn0033791
MGI:MGI:101766
PANTHER:PTN002521290

F

Seeded From UniProt

complete

protected

involved_in

GO:0016477

cell migration

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347244
MGI:MGI:96969
PANTHER:PTN002814495
RGD:3082
ZFIN:ZDB-GENE-041014-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0016055

Wnt signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101766
PANTHER:PTN002521290

P

Seeded From UniProt

complete

protected

involved_in

GO:0007399

nervous system development

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347244
MGI:MGI:96969
PANTHER:PTN002814495
RGD:3082
WB:WBGene00020504
ZFIN:ZDB-GENE-041014-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0283499
MGI:MGI:104757
MGI:MGI:109378
MGI:MGI:1096337
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95278
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95523
MGI:MGI:95524
MGI:MGI:95525
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96575
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97531
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99216
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2612
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
RGD:69323
UniProtKB:A6QR62
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:P54764
UniProtKB:Q02763
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q15375
UniProtKB:Q16288
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
WB:WBGene00001184
WB:WBGene00006868
ZFIN:ZDB-GENE-020503-1
ZFIN:ZDB-GENE-020503-2
ZFIN:ZDB-GENE-060503-14
ZFIN:ZDB-GENE-070713-2
ZFIN:ZDB-GENE-980526-255
ZFIN:ZDB-GENE-980526-326
ZFIN:ZDB-GENE-990415-62

P

Seeded From UniProt

complete

protected

involved_in

GO:0006909

phagocytosis

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347244
PANTHER:PTN001231011
RGD:69283
UniProtKB:P30530
UniProtKB:Q12866

P

Seeded From UniProt

complete

protected

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0011829
FB:FBgn0015380
FB:FBgn0032006
FB:FBgn0283499
MGI:MGI:103581
MGI:MGI:104771
MGI:MGI:109378
MGI:MGI:98277
MGI:MGI:99611
PANTHER:PTN002356460
RGD:1560587
RGD:3213
RGD:3214
RGD:70957
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q02763
UniProtKB:Q16620
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00000898

C

Seeded From UniProt

complete

protected

enables

GO:0005008

hepatocyte growth factor-activated receptor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96969
PANTHER:PTN002814515
RGD:3082

F

Seeded From UniProt

complete

protected

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003733
FB:FBgn0040505
FB:FBgn0283499
MGI:MGI:109378
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95524
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07333
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00006868
WB:WBGene00020504
ZFIN:ZDB-GENE-980526-255

F

Seeded From UniProt

complete

protected

involved_in

GO:0001889

liver development

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96969
PANTHER:PTN002814515
RGD:3082
ZFIN:ZDB-GENE-041014-1

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:2001028

positive regulation of endothelial cell chemotaxis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1905098

negative regulation of guanyl-nucleotide exchange factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1901299

negative regulation of hydrogen peroxide-mediated programmed cell death

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1900745

positive regulation of p38MAPK cascade

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1900407

regulation of cellular response to oxidative stress

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0072593

reactive oxygen species metabolic process

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071635

negative regulation of transforming growth factor beta production

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071526

semaphorin-plexin signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0070495

negative regulation of thrombin-activated receptor signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0061436

establishment of skin barrier

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0060665

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

PMID:14517989

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0060076

excitatory synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0060048

cardiac muscle contraction

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0055013

cardiac muscle cell development

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051497

negative regulation of stress fiber assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051450

myoblast proliferation

PMID:11061428

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1858021

P

  • occurs_in:(EMAPA:18521)
  • acts_on_population_of:(CL:0000515)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0050918

positive chemotaxis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0050775

positive regulation of dendrite morphogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048754

branching morphogenesis of an epithelial tube

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048012

hepatocyte growth factor receptor signaling pathway

PMID:15314156

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

PMID:15314156

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045840

positive regulation of mitotic nuclear division

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045740

positive regulation of DNA replication

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

enables

GO:0044877

protein-containing complex binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

enables

GO:0043548

phosphatidylinositol 3-kinase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

enables

GO:0043274

phospholipase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0042593

glucose homeostasis

PMID:16049329

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2176227,MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

part_of

GO:0036126

sperm flagellum

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0035024

negative regulation of Rho protein signal transduction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0033138

positive regulation of peptidyl-serine phosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0032675

regulation of interleukin-6 production

PMID:21072211

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0031116

positive regulation of microtubule polymerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030534

adult behavior

PMID:12397180

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2450967

P

Seeded From UniProt

complete

protected

part_of

GO:0030425

dendrite

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030317

flagellated sperm motility

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

enables

GO:0019903

protein phosphatase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:7565774

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0014902

myotube differentiation

PMID:7651534

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1857655

P

occurs_in:(EMAPA:17883)|occurs_in:(EMAPA:16405)|occurs_in:(EMAPA:17701)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0014812

muscle cell migration

PMID:7651534

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1857655

P

occurs_in:(EMAPA:16184)|occurs_in:(EMAPA:16405)

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010976

positive regulation of neuron projection development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010828

positive regulation of glucose transmembrane transport

PMID:16049329

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2176227,MGI:MGI:3041135

P

  • regulates_o_occurs_in:(EMAPA:32927)
  • regulates_o_occurs_in:(CL:0000169)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010801

negative regulation of peptidyl-threonine phosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010629

negative regulation of gene expression

PMID:23994610

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3041135

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0010628

positive regulation of gene expression

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

part_of

GO:0009925

basal plasma membrane

PMID:15314156

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

C

Seeded From UniProt

complete

protected

enables

GO:0008013

beta-catenin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007519

skeletal muscle tissue development

PMID:7651534

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1857655

P

results_in_development_of:(EMAPA:17883)|results_in_development_of:(EMAPA:16405)|results_in_development_of:(EMAPA:17701)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007517

muscle organ development

PMID:15376315

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:97487

P

results_in_development_of:(EMAPA:18276)|results_in_development_of:(EMAPA:18277)|results_in_development_of:(EMAPA:17701)|results_in_development_of:(EMAPA:19070)|results_in_development_of:(EMAPA:19067)|results_in_development_of:(EMAPA:18177)|results_in_development_of:(EMAPA:18179)|results_in_development_of:(EMAPA:18180)|results_in_development_of:(EMAPA:18178)|results_in_development_of:(EMAPA:16405)|results_in_development_of:(EMAPA:17844)|results_in_development_of:(EMAPA:18190)|results_in_development_of:(EMAPA:18276)|results_in_development_of:(EMAPA:18277)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007517

muscle organ development

PMID:15376315

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1858019

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007420

brain development

PMID:12397180

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2450967

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

part_of

GO:0005615

extracellular space

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

C

Seeded From UniProt

complete

protected

enables

GO:0005008

hepatocyte growth factor-activated receptor activity

PMID:15314156

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0005008

hepatocyte growth factor-activated receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

F

Seeded From UniProt

complete

protected

enables

GO:0004672

protein kinase activity

PMID:7651534

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001890

placenta development

PMID:7651534

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1857655

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001889

liver development

PMID:7651534

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1857655

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001886

endothelial cell morphogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P08581

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001764

neuron migration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0000187

activation of MAPK activity

PMID:15314156

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q8BUE7

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3082

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004713

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004713

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004713

P

Seeded From UniProt

complete

protected

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

protected

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

protected

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020635

F

Seeded From UniProt

complete

protected

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016244

F

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR016244
InterPro:IPR017441

F

Seeded From UniProt

complete

protected

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR020635

P

Seeded From UniProt

complete

protected

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016244

P

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016244

C

Seeded From UniProt

complete

protected

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.10.1

F

Seeded From UniProt

complete

protected

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

protected

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

protected

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

protected

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

protected

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete




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