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HUMAN:CAV2

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0019065

receptor-mediated endocytosis of virus by host

PMID:21047970

ECO:0000316

UniProtKB:O60840


P

Fig. 2EFG Part of the caveola/lipid raft-mediated entry pathway

complete
CACAO 2437

protected

involved_in

GO:0044791

positive regulation by host of viral release from host cell

PMID:25556234

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0044794

positive regulation by host of viral process

PMID:25556234

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:25556234

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0019065

receptor-mediated endocytosis of virus by host cell

PMID:21047970

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:O60840

P

Seeded From UniProt

complete

protected

involved_in

GO:0043410

positive regulation of MAPK cascade

PMID:20455999

ECO:0000314

direct assay evidence used in manual assertion

P

part_of:(GO:0008286)

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:20455999

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

colocalizes_with

GO:0005925

focal adhesion

PMID:12091389

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:2000008)

Seeded From UniProt

complete

protected

involved_in

GO:0043547

positive regulation of GTPase activity

PMID:8552590

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:8552590

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:9361015

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000115)
  • part_of:(UBERON:0000014)
  • part_of:(GO:0016323)|part_of:(CL:0000115)
  • part_of:(UBERON:0000014)
  • part_of:(GO:0016324)

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:12743374

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(GO:0016323)

Seeded From UniProt

complete

protected

involved_in

GO:0070836

caveola assembly

PMID:12743374

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(GO:0016323)

Seeded From UniProt

complete

protected

part_of

GO:0030133

transport vesicle

GO_REF:0000054

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0070836

caveola assembly

PMID:12633858

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0060161

positive regulation of dopamine receptor signaling pathway

PMID:15569306

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:18081315

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0048278

vesicle docking

PMID:12743374

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

PMID:15569306

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0016050

vesicle organization

PMID:12743374

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007088

regulation of mitotic nuclear division

PMID:18081315

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006906

vesicle fusion

PMID:12743374

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:18081315

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:15703204

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:15569306

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005794

Golgi apparatus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q2IBC5

C

Seeded From UniProt

complete

protected

part_of

GO:0045121

membrane raft

PMID:11294831

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0048741

skeletal muscle fiber development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WVC3

P

Seeded From UniProt

complete

protected

involved_in

GO:0007029

endoplasmic reticulum organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WVC3

P

Seeded From UniProt

complete

protected

involved_in

GO:0007005

mitochondrion organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WVC3

P

Seeded From UniProt

complete

protected

involved_in

GO:0001937

negative regulation of endothelial cell proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9WVC3

P

Seeded From UniProt

complete

protected

involved_in

GO:0070836

caveola assembly

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107570
PANTHER:PTN000851526
UniProtKB:P51636
UniProtKB:P56539
UniProtKB:Q03135

P

Seeded From UniProt

complete

protected

enables

GO:0060090

molecular adaptor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000851526
RGD:2281
UniProtKB:P56539

F

Seeded From UniProt

complete

protected

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090157
UniProtKB:P51636

C

Seeded From UniProt

complete

protected

involved_in

GO:0043410

positive regulation of MAPK cascade

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090157
RGD:620348
UniProtKB:P51636

P

Seeded From UniProt

complete

protected

colocalizes_with

GO:0042383

sarcolemma

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107570
PANTHER:PTN000090155
RGD:2281
UniProtKB:P56539
UniProtKB:P79132
UniProtKB:Q2KI43
UniProtKB:Q66WT7

C

Seeded From UniProt

complete

protected

colocalizes_with

GO:0032991

protein-containing complex

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000090155
RGD:2280
RGD:2281
RGD:620348
UniProtKB:P51636
UniProtKB:Q03135

C

Seeded From UniProt

complete

protected

part_of

GO:0031410

cytoplasmic vesicle

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090157
UniProtKB:P51636

C

Seeded From UniProt

complete

protected

involved_in

GO:0030154

cell differentiation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090155
RGD:2281

P

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107571
PANTHER:PTN000090157

F

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090157
RGD:620348
UniProtKB:P51636

P

Seeded From UniProt

complete

protected

colocalizes_with

GO:0005925

focal adhesion

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000090155
RGD:2280
UniProtKB:P51636
UniProtKB:Q03135

C

Seeded From UniProt

complete

protected

colocalizes_with

GO:0005901

caveola

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107570
PANTHER:PTN000851526
RGD:2280
RGD:2281
RGD:620348
UniProtKB:P33724
UniProtKB:P35431
UniProtKB:P51636
UniProtKB:P79132
UniProtKB:Q03135
UniProtKB:Q2KI43
UniProtKB:Q66WT7
UniProtKB:Q6RVA9

C

Seeded From UniProt

complete

protected

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000851526
UniProtKB:P51636
WB:WBGene00000301

C

Seeded From UniProt

complete

protected

part_of

GO:0005794

Golgi apparatus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090157
RGD:620348

C

Seeded From UniProt

complete

protected

colocalizes_with

GO:0005737

cytoplasm

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000851526
RGD:2280
RGD:2281
RGD:620348

C

Seeded From UniProt

complete

protected

enables

GO:0005198

structural molecule activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000851526
UniProtKB:P33724
UniProtKB:Q03135

F

Seeded From UniProt

complete

protected

involved_in

GO:0001937

negative regulation of endothelial cell proliferation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107571
PANTHER:PTN000090157
RGD:620348

P

Seeded From UniProt

complete

protected

enables

GO:0042803

protein homodimerization activity

PMID:8552590

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0032991

protein-containing complex

PMID:24013648

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0031410

cytoplasmic vesicle

PMID:22792322

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

PMID:24013648

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005887

integral component of plasma membrane

PMID:8552590

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:15788404

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0097110

scaffold protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

F

Seeded From UniProt

complete

protected

enables

GO:0060090

molecular adaptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

F

Seeded From UniProt

complete

protected

involved_in

GO:0051259

protein complex oligomerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

involved_in

GO:0048741

skeletal muscle fiber development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

F

Seeded From UniProt

complete

protected

part_of

GO:0032991

protein-containing complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

enables

GO:0030674

protein binding, bridging

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

F

Seeded From UniProt

complete

protected

involved_in

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

involved_in

GO:0007029

endoplasmic reticulum organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

involved_in

GO:0007005

mitochondrion organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

part_of

GO:0005925

focal adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

part_of

GO:0002080

acrosomal membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

C

Seeded From UniProt

complete

protected

involved_in

GO:0001938

positive regulation of endothelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

involved_in

GO:0001937

negative regulation of endothelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVC3
ensembl:ENSMUSP00000000058

P

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033306

C

Seeded From UniProt

complete

protected

involved_in

GO:0070836

caveola assembly

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001612
InterPro:IPR033306

P

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:15569306

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0031748

D1 dopamine receptor binding

PMID:15569306

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P21728

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:15569306

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:15569306

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

protected

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

protected

part_of

GO:0005901

caveola

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0035

C

Seeded From UniProt

complete

protected

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete




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