GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

TableEdit

Jump to: navigation, search

PMID:18398480

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

Citation

Jayaram, SA, Senti, KA, Tiklová, K, Tsarouhas, V, Hemphälä, J and Samakovlis, C (2008) COPI vesicle transport is a common requirement for tube expansion in Drosophila. PLoS ONE 3:e1964

Abstract

Tube expansion defects like stenoses and atresias cause devastating human diseases. Luminal expansion during organogenesis begins to be elucidated in several systems but we still lack a mechanistic view of the process in many organs. The Drosophila tracheal respiratory system provides an amenable model to study tube size regulation. In the trachea, COPII anterograde transport of luminal proteins is required for extracellular matrix assembly and the concurrent tube expansion.

Links

PubMed PMC2276865 Online version:10.1371/journal.pone.0001964

Keywords

Animals; Biological Transport; Coat Protein Complex I/metabolism; Coatomer Protein/metabolism; Drosophila/metabolism; Drosophila Proteins/metabolism; Endoplasmic Reticulum/metabolism; Extracellular Matrix/metabolism; Golgi Apparatus/metabolism; Models, Biological; Mutation; Phenotype; Respiratory System; Trachea/metabolism

public



Cancel