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Ye, D, Meurs, I, Ohigashi, M, Calpe-Berdiel, L, Habets, KL, Zhao, Y, Kubo, Y, Yamaguchi, A, Van Berkel, TJ, Nishi, T and Van Eck, M (2010) Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice. Biochem. Biophys. Res. Commun. 395:387-94
To determine the role of macrophage ATP-binding cassette transporter A5 (ABCA5) in cellular cholesterol homeostasis and atherosclerotic lesion development.
ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Animals; Atherosclerosis/metabolism; Cholesterol/genetics; Cholesterol/metabolism; Female; Lipids/blood; Macrophages/metabolism; Male; Mice; Mice, Knockout; Receptors, LDL/genetics