GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

TableEdit

Jump to: navigation, search

PMID:19915591

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

Citation

Ausin, I, Mockler, TC, Chory, J and Jacobsen, SE (2009) IDN1 and IDN2 are required for de novo DNA methylation in Arabidopsis thaliana. Nat. Struct. Mol. Biol. 16:1325-7

Abstract

DNA methylation is an epigenetic mark affecting genes and transposons. Screening for mutants that fail to establish DNA methylation yielded two we termed "involved in de novo" (idn) 1 and 2. IDN1 encodes DMS3, an SMC-related protein, and IDN2 encodes a previously unknown double-stranded RNA-binding protein with homology to SGS3. IDN1 and IDN2 control de novo methylation and small interfering RNA (siRNA)-mediated maintenance methylation and are components of the RNA-directed DNA methylation pathway.

Links

PubMed PMC2842998 Online version:10.1038/nsmb.1690

Keywords

Arabidopsis/physiology; Arabidopsis Proteins/genetics; Arabidopsis Proteins/physiology; Chromosomal Proteins, Non-Histone/genetics; Chromosomal Proteins, Non-Histone/physiology; DNA Methylation; RNA-Binding Proteins/genetics; RNA-Binding Proteins/physiology

public



Cancel