GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki
Lin, H (2002) The stem-cell niche theory: lessons from flies. Nat. Rev. Genet. 3:931-40
Stem cells are characterized by their ability to self-renew and to produce numerous differentiated cell types, and are directly responsible for generating and maintaining tissues and organs. This property has long been attributed to the instructive signals that stem cells receive from their microenvironment - the so-called 'stem-cell niche'. Studies of stem cells in the Drosophila gonad have yielded much exciting insight into the structure of the niche and the signalling pathways that it produces to regulate the self-renewal of stem cells. These findings are illuminating our understanding of the self-renewing mechanisms of tissue stem cells in general.
Animals; Cell Differentiation/physiology; Drosophila/genetics; Drosophila/metabolism; Female; Male; Ovary/metabolism; Signal Transduction/genetics; Signal Transduction/physiology; Stem Cells/cytology; Stem Cells/physiology; Testis/metabolism