GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com


Jump to: navigation, search


You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor


Pinto, JP, Conceição, NM, Viegas, CS, Leite, RB, Hurst, LD, Kelsh, RN and Cancela, ML (2005) Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro. J. Bone Miner. Res. 20:1440-53


The zebrafish runx2b transcription factor is an ortholog of RUNX2 and is highly conserved at the structural level. The runx2b pebp2alphaA2 isoform induces osteocalcin gene expression by binding to a specific region of the promoter and seems to have been selectively conserved in the teleost lineage.


PubMed Online version:10.1359/JBMR.050318


Amino Acid Sequence; Animals; Conserved Sequence; Evolution, Molecular; Gene Expression Regulation; Genes, Reporter/genetics; Molecular Sequence Data; Osteocalcin/genetics; Phylogeny; Promoter Regions, Genetic; Protein Conformation; Protein Isoforms/classification; Protein Isoforms/genetics; Protein Isoforms/metabolism; Transcription Factors/classification; Transcription Factors/genetics; Transcription Factors/metabolism; Up-Regulation; Zebrafish/genetics; Zebrafish/metabolism; Zebrafish Proteins/classification; Zebrafish Proteins/genetics; Zebrafish Proteins/metabolism