GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki
Fujii, H, Krietsch, WK and Yoshida, A (1980) A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency. J. Biol. Chem. 255:6421-3
The structural abnormality of the phosphoglycerate kinase variant, PGK München, associated with red cell enzyme deficiency and heat instability, was elucidated by a microscale peptide-mapping method. A single amino acid substitution, from aspartic acid in the normal enzyme to asparagine in the variant enzyme, was found. From the known amino acid sequence of normal human phosphoglycerate kinase, the substitution is in the aspartic acid residue located at 268th position from the NH2-terminal of the protein.
Amino Acid Sequence; Amino Acids/analysis; Asparagine/analysis; Aspartic Acid/analysis; Erythrocytes/enzymology; Genetic Variation; Humans; Metabolism, Inborn Errors/enzymology; Peptides/analysis; Phosphoglycerate Kinase/analysis; Phosphoglycerate Kinase/deficiency; Phosphoglycerate Kinase/genetics