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MOUSE:WDR5

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

part_of

GO:0071339

MLL1 complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

involved_in

GO:0051568

histone H3-K4 methylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

contributes_to

GO:0046972

histone acetyltransferase activity (H4-K16 specific)

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

contributes_to

GO:0043996

histone acetyltransferase activity (H4-K8 specific)

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

contributes_to

GO:0043995

histone acetyltransferase activity (H4-K5 specific)

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

involved_in

GO:0043984

histone H4-K16 acetylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

involved_in

GO:0043982

histone H4-K8 acetylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

involved_in

GO:0043981

histone H4-K5 acetylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:15860628

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0000123

histone acetyltransferase complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

involved_in

GO:0051568

histone H3-K4 methylation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0040066
MGI:MGI:2155884
PANTHER:PTN001483578
UniProtKB:P61964
WB:WBGene00006474

P

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0040066
PANTHER:PTN001483578
TAIR:locus:2097435
UniProtKB:P61964

C

Seeded From UniProt

complete

protected

enables

GO:0042393

histone binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001483578
TAIR:locus:2097435
UniProtKB:P61964

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0040066
MGI:MGI:2155884
PANTHER:PTN001483578
RGD:1305159
TAIR:locus:2097435
UniProtKB:P61964
WB:WBGene00006474

C

Seeded From UniProt

complete

protected

part_of

GO:0071339

MLL1 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051568

histone H3-K4 methylation

PMID:24051374

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051568

histone H3-K4 methylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

contributes_to

GO:0046972

histone acetyltransferase activity (H4-K16 specific)

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

part_of

GO:0044666

MLL3/4 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

contributes_to

GO:0043996

histone acetyltransferase activity (H4-K8 specific)

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

contributes_to

GO:0043995

histone acetyltransferase activity (H4-K5 specific)

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043984

histone H4-K16 acetylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043982

histone H4-K8 acetylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043981

histone H4-K5 acetylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043966

histone H3 acetylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

P

Seeded From UniProt

complete

protected

contributes_to

GO:0042800

histone methyltransferase activity (H3-K4 specific)

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0035948

positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter

PMID:24051374

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1343094
MGI:MGI:95674

P

  • occurs_in:(EMAPA:16846)
  • regulates_o_occurs_in:(EMAPA:16846)
  • has_regulation_target:(MGI:MGI:97501)
  • has_regulation_target:(MGI:MGI:95607)

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

PMID:17500065

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

enables

GO:0035064

methylated histone binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0031175

neuron projection development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1305159

P

Seeded From UniProt

complete

protected

part_of

GO:0005671

Ada2/Gcn5/Ada3 transcription activator complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:22514746

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:19103755

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:17500065

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1305159

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001501

skeletal system development

PMID:11551928

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0000123

histone acetyltransferase complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61964

C

Seeded From UniProt

complete

protected

part_of

GO:0071339

MLL1 complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

involved_in

GO:0051568

histone H3-K4 methylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

P

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

enables

GO:0046972

histone acetyltransferase activity (H4-K16 specific)

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

F

Seeded From UniProt

complete

protected

part_of

GO:0044666

MLL3/4 complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

enables

GO:0043996

histone acetyltransferase activity (H4-K8 specific)

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

F

Seeded From UniProt

complete

protected

enables

GO:0043995

histone acetyltransferase activity (H4-K5 specific)

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

F

Seeded From UniProt

complete

protected

involved_in

GO:0043984

histone H4-K16 acetylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

P

Seeded From UniProt

complete

protected

involved_in

GO:0043982

histone H4-K8 acetylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

P

Seeded From UniProt

complete

protected

involved_in

GO:0043981

histone H4-K5 acetylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

P

Seeded From UniProt

complete

protected

involved_in

GO:0043966

histone H3 acetylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

P

Seeded From UniProt

complete

protected

enables

GO:0042800

histone methyltransferase activity (H3-K4 specific)

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

F

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

enables

GO:0035064

methylated histone binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

F

Seeded From UniProt

complete

protected

part_of

GO:0005671

Ada2/Gcn5/Ada3 transcription activator complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

part_of

GO:0000123

histone acetyltransferase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61964
ensembl:ENSP00000351446

C

Seeded From UniProt

complete

protected

involved_in

GO:0031175

neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q498M4
ensembl:ENSRNOP00000011556

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q498M4
ensembl:ENSRNOP00000011556

C

Seeded From UniProt

complete

protected

part_of

GO:0005671

Ada2/Gcn5/Ada3 transcription activator complex

PMID:20508642

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

Reactome:R-MMU-6810170
Reactome:R-MMU-6810169
Reactome:R-MMU-6810150
Reactome:R-MMU-5693628
Reactome:R-MMU-5621012
Reactome:R-MMU-5621004
Reactome:R-MMU-5619441
Reactome:R-MMU-5619440
Reactome:R-MMU-5619437
Reactome:R-MMU-5619436
Reactome:R-MMU-5619434
Reactome:R-MMU-5619430
Reactome:R-MMU-5619424
Reactome:R-MMU-5619411
Reactome:R-MMU-5617990
Reactome:R-MMU-5617960

ECO:0000304

author statement supported by traceable reference used in manual assertion
















C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete




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