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HUMAN:SET1A

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0097692

histone H3-K4 monomethylation

PMID:25561738

ECO:0000314

P

Figure 2C

complete
CACAO 11801

public

GO:0044648

histone H3-K4 dimethylation

PMID:25561738

ECO:0000314

P

Figure 2C

complete
CACAO 11802

public

GO:0080182

histone H3-K4 trimethylation

PMID:25561738

ECO:0000314

P

Figure 2C

complete
CACAO 11803

protected

involved_in

GO:1902036

regulation of hematopoietic stem cell differentiation

PMID:27141965

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0008134

transcription factor binding

PMID:27141965

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P22415

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:22723415

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0008013

beta-catenin binding

PMID:22723415

ECO:0000314

direct assay evidence used in manual assertion

F

  • occurs_in:(GO:0005634)
  • has_direct_input:(PR:000002198)

Seeded From UniProt

complete

protected

involved_in

GO:1902275

regulation of chromatin organization

PMID:27141965

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0000790

nuclear chromatin

PMID:27141965

ECO:0000314

direct assay evidence used in manual assertion

C

  • coincident_with:(SO:0000167)
  • coincident_with:(ENSEMBL:ENSG00000244734)

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

PMID:17998332

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

PMID:18838538

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0042800

histone methyltransferase activity (H3-K4 specific)

PMID:20862685

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

PMID:17355966

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0035097

histone methyltransferase complex

PMID:17500065

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:17500065

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0016607

nuclear speck

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0034968

histone lysine methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0018024

P

Seeded From UniProt

complete

protected

involved_in

GO:0034968

histone lysine methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0018024

P

Seeded From UniProt

complete

protected

involved_in

GO:0051568

histone H3-K4 methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0042800

P

Seeded From UniProt

complete

protected

involved_in

GO:0051568

histone H3-K4 methylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0042800

P

Seeded From UniProt

complete

protected

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000504
InterPro:IPR035979

F

Seeded From UniProt

complete

protected

enables

GO:0018024

histone-lysine N-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037841

F

Seeded From UniProt

complete

protected

enables

GO:0042800

histone methyltransferase activity (H3-K4 specific)

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037841

F

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037841

C

Seeded From UniProt

complete

protected

enables

GO:0018024

histone-lysine N-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.43

F

Seeded From UniProt

complete

protected

part_of

GO:0048188

Set1C/COMPASS complex

PMID:27141965

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0045652

regulation of megakaryocyte differentiation

Reactome:R-HSA-8936459

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-8937050
Reactome:R-HSA-8937037
Reactome:R-HSA-8937016
Reactome:R-HSA-8936979
Reactome:R-HSA-8936621
Reactome:R-HSA-8936616
Reactome:R-HSA-8936481
Reactome:R-HSA-8935740
Reactome:R-HSA-5637686
Reactome:R-HSA-5244692
Reactome:R-HSA-5159245

ECO:0000304

author statement supported by traceable reference used in manual assertion











C

Seeded From UniProt

complete

protected

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

protected

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

protected

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

protected

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

protected

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

protected

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

protected

part_of

GO:0016607

nuclear speck

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0186

C

Seeded From UniProt

complete




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