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MOUSE:PPARD

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

part_of

GO:0000790

nuclear chromatin

PMID:20445066

ECO:0000314

direct assay evidence used in manual assertion

C

  • coincident_with:(SO:0000167)
  • coincident_with:(ENSEMBL:ENSMUSG00000093007)

Seeded From UniProt

complete

protected

involved_in

GO:1902894

negative regulation of pri-miRNA transcription by RNA polymerase II

PMID:20445066

ECO:0000314

direct assay evidence used in manual assertion

P

regulates_transcription_of:(ENSEMBL:ENSMUSG00000093007)

Seeded From UniProt

complete

protected

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:20445066

ECO:0000314

direct assay evidence used in manual assertion

F

has_regulation_target:(ENSEMBL:ENSMUSG00000093007)

Seeded From UniProt

complete

protected

involved_in

GO:0043415

positive regulation of skeletal muscle tissue regeneration

PMID:22040534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0045662

negative regulation of myoblast differentiation

PMID:22040534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0014842

regulation of skeletal muscle satellite cell proliferation

PMID:22040534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0010628

positive regulation of gene expression

PMID:22040534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:2000288

positive regulation of myoblast proliferation

PMID:22040534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0070539

linoleic acid binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

involved_in

GO:0050796

regulation of insulin secretion

PMID:14676330

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03181

P

Seeded From UniProt

complete

protected

involved_in

GO:0015908

fatty acid transport

PMID:14676330

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0008289

lipid binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

enables

GO:0008144

drug binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

involved_in

GO:0006635

fatty acid beta-oxidation

PMID:14676330

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0004879

nuclear receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

part_of

GO:0090575

RNA polymerase II transcription factor complex

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1352462
PANTHER:PTN000637751
UniProtKB:P11473
UniProtKB:P37231
UniProtKB:Q13133

C

Seeded From UniProt

complete

protected

involved_in

GO:0050728

negative regulation of inflammatory response

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000638181
RGD:3370

P

Seeded From UniProt

complete

protected

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
MGI:MGI:104740
MGI:MGI:1352462
MGI:MGI:1352463
MGI:MGI:1352464
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
MGI:MGI:98742
MGI:MGI:98743
PANTHER:PTN000637751
RGD:3371
RGD:3857
RGD:61906
RGD:628831
UniProtKB:O62807
UniProtKB:O75469
UniProtKB:P10276
UniProtKB:P11473
UniProtKB:P37231
UniProtKB:P55055
UniProtKB:Q07869
UniProtKB:Q13133
UniProtKB:Q14994
UniProtKB:Q8JHU1
UniProtKB:Q96RI1
WB:WBGene00000908

P

Seeded From UniProt

complete

protected

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000637985

P

Seeded From UniProt

complete

protected

enables

GO:0038023

signaling receptor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN000637751

F

Seeded From UniProt

complete

protected

involved_in

GO:0033993

response to lipid

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN001941333
RGD:3371

P

Seeded From UniProt

complete

protected

involved_in

GO:0033993

response to lipid

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN001182169
RGD:3371

P

Seeded From UniProt

complete

protected

enables

GO:0030374

nuclear receptor transcription coactivator activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000637751
UniProtKB:O62807
UniProtKB:P37231

F

Seeded From UniProt

complete

protected

involved_in

GO:0030154

cell differentiation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
PANTHER:PTN000637751

P

Seeded From UniProt

complete

protected

involved_in

GO:0019216

regulation of lipid metabolic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000637985
RGD:3371

P

Seeded From UniProt

complete

protected

involved_in

GO:0010887

negative regulation of cholesterol storage

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:P37231
UniProtKB:Q07869

P

Seeded From UniProt

complete

protected

involved_in

GO:0009755

hormone-mediated signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001941333
UniProtKB:P10827

P

Seeded From UniProt

complete

protected

enables

GO:0008289

lipid binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN001182169
UniProtKB:Q03181
UniProtKB:Q07869

F

Seeded From UniProt

complete

protected

enables

GO:0008144

drug binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:P37231
UniProtKB:Q03181
UniProtKB:Q07869

F

Seeded From UniProt

complete

protected

enables

GO:0008134

transcription factor binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97856
PANTHER:PTN000637751
RGD:3371
RGD:3534
UniProtKB:P10276
UniProtKB:P10827
UniProtKB:P37231
UniProtKB:Q03181
UniProtKB:Q07869
ZFIN:ZDB-GENE-000210-31

F

Seeded From UniProt

complete

protected

involved_in

GO:0007275

multicellular organism development

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103076
PANTHER:PTN000637751

P

Seeded From UniProt

complete

protected

involved_in

GO:0006631

fatty acid metabolic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN001182169
RGD:3369

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
FB:FBgn0000568
MGI:MGI:101884
MGI:MGI:1346307
MGI:MGI:1352462
MGI:MGI:1352463
MGI:MGI:2444210
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97858
MGI:MGI:98742
MGI:MGI:98743
PANTHER:PTN000637751
RGD:3369
RGD:3370
RGD:3371
RGD:3534
RGD:3857
RGD:61909
RGD:621400
RGD:628831
UniProtKB:O62807
UniProtKB:P04625
UniProtKB:P10276
UniProtKB:P10826
UniProtKB:P10827
UniProtKB:P11473
UniProtKB:P13631
UniProtKB:P37231
UniProtKB:P55055
UniProtKB:P68306
UniProtKB:Q07869
UniProtKB:Q13133
UniProtKB:Q14995
WB:WBGene00000908
WB:WBGene00003607
WB:WBGene00004786
ZFIN:ZDB-GENE-990415-263

C

Seeded From UniProt

complete

protected

enables

GO:0005504

fatty acid binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
RGD:3370

F

Seeded From UniProt

complete

public

GO:2000288

positive regulation of myoblast proliferation

PMID:22040534

ECO:0000315

P

Fig. 2BE, and Fig. 3

complete
CACAO 2771

protected

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
PANTHER:PTN001182169

F

Seeded From UniProt

complete

public

GO:0010628

positive regulation of gene expression

PMID:22040534

ECO:0000315

P

Fig. 1EF

complete
CACAO 2772

protected

enables

GO:0001103

RNA polymerase II repressing transcription factor binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:Q07869

F

Seeded From UniProt

complete

public

GO:0014842

regulation of satellite cell proliferation

PMID:22040534

ECO:0000315

P

Fig. 2ACD; positive regulation

complete
CACAO 2773

protected

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
PANTHER:PTN000637751
RGD:61906

F

Seeded From UniProt

complete

public

GO:0045662

negative regulation of myoblast differentiation

PMID:22040534

ECO:0000315

P

Fig. 2E

complete
CACAO 2774

protected

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
FB:FBgn0015240
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
PANTHER:PTN000637751
UniProtKB:O75469
UniProtKB:P20393
UniProtKB:Q14994
UniProtKB:Q96RI1
WB:WBGene00004786

F

Seeded From UniProt

complete

protected

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
MGI:MGI:98742
PANTHER:PTN000637751
RGD:628827
UniProtKB:Q96RI1

F

Seeded From UniProt

complete

public

GO:0043415

positive regulation of skeletal muscle tissue regeneration

PMID:22040534

ECO:0000315

P

Fig. 4(A-D)

complete
CACAO 2775

protected

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
MGI:MGI:2449205
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
MGI:MGI:98743
PANTHER:PTN001941333
UniProtKB:P20393
UniProtKB:P37231
UniProtKB:Q07869
WB:WBGene00004786

P

Seeded From UniProt

complete

public

GO:2000288

positive regulation of myoblast proliferation

PMID:22040534

ECO:0000315

P

Figure 3D, Ppard cKO muscle showed reduced growth rate of myoblasts cells compared to wild type.

complete
CACAO 3208

protected

acts_upstream_of_or_within

GO:0097755

positive regulation of blood vessel diameter

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0097190

apoptotic signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071456

cellular response to hypoxia

PMID:24011070

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:106918
MGI:MGI:2676890
MGI:MGI:3618742

P

occurs_in:(EMAPA:32688)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0071222

cellular response to lipopolysaccharide

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

enables

GO:0070539

linoleic acid binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0060612

adipose tissue development

PMID:11756685

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2386684

P

results_in_development_of:(EMAPA:35112)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051546

keratinocyte migration

PMID:11514592

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3575004

P

Seeded From UniProt

complete

protected

enables

GO:0051059

NF-kappaB binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0050728

negative regulation of inflammatory response

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0050680

negative regulation of epithelial cell proliferation

PMID:14758356

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:88039

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048662

negative regulation of smooth muscle cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

PMID:10385625

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P28700

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045684

positive regulation of epidermis development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0045598

regulation of fat cell differentiation

PMID:11756685

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2386684

P

  • occurs_in:(EMAPA:19209)
  • results_in_acquisition_of_features_of:(CL:0000136)|occurs_in(EMAPA:35926)
  • results_in_acquisition_of_features_of:(CL:0000136)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043616

keratinocyte proliferation

PMID:11511099

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3575004

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0043066

negative regulation of apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0042127

regulation of cell population proliferation

PMID:15380519

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:88039

P

occurs_in:(EMAPA:32874)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0042127

regulation of cell population proliferation

PMID:10866668

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1889516

P

acts_on_population_of:(CL:0000362)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0042060

wound healing

PMID:11514592

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3575004

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0032966

negative regulation of collagen biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0032024

positive regulation of insulin secretion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0031589

cell-substrate adhesion

PMID:11514592

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3575004

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030308

negative regulation of cell growth

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030154

cell differentiation

PMID:16581799

ECO:0000315

mutant phenotype evidence used in manual assertion

P

results_in_acquisition_of_features_of:(CL:0000351)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0030154

cell differentiation

PMID:16581799

ECO:0000314

direct assay evidence used in manual assertion

P

results_in_acquisition_of_features_of:(CL:0000351)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0019395

fatty acid oxidation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0014912

negative regulation of smooth muscle cell migration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

PMID:16581799

ECO:0000314

direct assay evidence used in manual assertion

P

  • regulates_o_occurs_in:(CL:0000351)|regulates_o_occurs_in:(EMAPA:16042)
  • regulates_o_occurs_in:(CL:0000351)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0009299

mRNA transcription

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0008654

phospholipid biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0008366

axon ensheathment

PMID:10866668

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1889516

P

Seeded From UniProt

complete

protected

enables

GO:0008289

lipid binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0008284

positive regulation of cell population proliferation

PMID:11756685

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2386684

P

Seeded From UniProt

complete

protected

enables

GO:0008144

drug binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

enables

GO:0008134

transcription factor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007566

embryo implantation

PMID:10385625

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006915

apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006776

vitamin A metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006629

lipid metabolic process

PMID:16581799

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3623147

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006629

lipid metabolic process

PMID:10866668

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1889516

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006629

lipid metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0006029

proteoglycan metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:10385625

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

C

Seeded From UniProt

complete

protected

enables

GO:0005504

fatty acid binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

F

Seeded From UniProt

complete

protected

enables

GO:0004879

nuclear receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

enables

GO:0003713

transcription coactivator activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3370

F

Seeded From UniProt

complete

protected

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03181

F

Seeded From UniProt

complete

protected

enables

GO:0003677

DNA binding

PMID:8041794

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001890

placenta development

PMID:11756685

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2386684

P

results_in_development_of:(EMAPA:16042)|results_in_development_of:(EMAPA:35689)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0001890

placenta development

PMID:11756685

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2386684

P

results_in_development_of:(EMAPA:16042)

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:8041794

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016501

P

Seeded From UniProt

complete

protected

involved_in

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004879

P

Seeded From UniProt

complete

protected

involved_in

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004879

P

Seeded From UniProt

complete

protected

involved_in

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004879

P

Seeded From UniProt

complete

protected

involved_in

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004879

P

Seeded From UniProt

complete

protected

involved_in

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004879

P

Seeded From UniProt

complete

protected

involved_in

GO:0043085

positive regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008047

P

Seeded From UniProt

complete

protected

involved_in

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003707

P

Seeded From UniProt

complete

protected

involved_in

GO:0097190

apoptotic signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

P

Seeded From UniProt

complete

protected

enables

GO:0070539

linoleic acid binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

P

Seeded From UniProt

complete

protected

enables

GO:0008289

lipid binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

enables

GO:0008144

drug binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

enables

GO:0008134

transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

involved_in

GO:0006915

apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

P

Seeded From UniProt

complete

protected

enables

GO:0004879

nuclear receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03181
ensembl:ENSP00000310928

F

Seeded From UniProt

complete

protected

involved_in

GO:0097755

positive regulation of blood vessel diameter

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0071222

cellular response to lipopolysaccharide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

enables

GO:0051059

NF-kappaB binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

F

Seeded From UniProt

complete

protected

involved_in

GO:0050728

negative regulation of inflammatory response

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0048662

negative regulation of smooth muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0046697

decidualization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0045684

positive regulation of epidermis development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0033189

response to vitamin A

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0032966

negative regulation of collagen biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0032024

positive regulation of insulin secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0030308

negative regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0019395

fatty acid oxidation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0014912

negative regulation of smooth muscle cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0014823

response to activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0010033

response to organic substance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0009749

response to glucose

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0009299

mRNA transcription

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0008654

phospholipid biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0007566

embryo implantation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0007507

heart development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0006776

vitamin A metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

involved_in

GO:0006029

proteoglycan metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

C

Seeded From UniProt

complete

protected

enables

GO:0005504

fatty acid binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

F

Seeded From UniProt

complete

protected

enables

GO:0003713

transcription coactivator activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99ND3
ensembl:ENSRNOP00000069522

F

Seeded From UniProt

complete

protected

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003075

F

Seeded From UniProt

complete

protected

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

protected

enables

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

protected

enables

GO:0004879

nuclear receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003074
InterPro:IPR003075

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003075

C

Seeded From UniProt

complete

protected

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003075
InterPro:IPR013088

P

Seeded From UniProt

complete

protected

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

complete

protected

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

PMID:15001550

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0046965

retinoid X receptor binding

PMID:15001550

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0016501

prostacyclin receptor activity

PMID:10754535

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0008047

enzyme activator activity

PMID:14677574

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0007566

embryo implantation

PMID:15001550
PMID:10754535

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0009987

cellular process

PMID:10866668

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0008544

epidermis development

PMID:10866668

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0004879

nuclear receptor activity

PMID:10866668

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

protected

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete




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