GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

TableEdit

Jump to: navigation, search

HUMAN:AKT2

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0004674

protein serine/threonine kinase activity

ECO:0000304

F

Source: ProtInc

Missing: reference

protected

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:10983986

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0010918

positive regulation of mitochondrial membrane potential

PMID:10983986

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:10983986

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

PMID:10983986

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

public

GO:2000144

positive regulation of DNA-dependent transcription, initiation

PMID:21297943

ECO:0000314

P

Figure 2A shows that the use of AKT2 siRNA, causes a decrease in the transcriptional levels of Cdk2, while scrambled or uninhibited AKT2 allows for transcriptional up-regulation of Ckd2.

complete
CACAO 7774

protected

part_of

GO:0032991

protein-containing complex

PMID:10983986

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0030335

positive regulation of cell migration

PMID:25428377

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:2000147

positive regulation of cell motility

PMID:17332325

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0046326

positive regulation of glucose import

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0045725

positive regulation of glycogen biosynthetic process

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0032869

cellular response to insulin stimulus

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0032000

positive regulation of fatty acid beta-oxidation

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0010907

positive regulation of glucose metabolic process

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0010748

negative regulation of long-chain fatty acid import across plasma membrane

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:16814735

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0090314

positive regulation of protein targeting to membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

P

Seeded From UniProt

complete

protected

involved_in

GO:0065002

intracellular protein transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

P

Seeded From UniProt

complete

protected

part_of

GO:0032587

ruffle membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

C

Seeded From UniProt

complete

protected

involved_in

GO:0031340

positive regulation of vesicle fusion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

P

Seeded From UniProt

complete

protected

part_of

GO:0005938

cell cortex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:20059950

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

PMID:16540465

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

PMID:16540465

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0001934

positive regulation of protein phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60823

P

Seeded From UniProt

complete

protected

involved_in

GO:0035556

intracellular signal transduction

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003744
FB:FBgn0010379
MGI:MGI:97601
PANTHER:PTN000683254
PomBase:SPAC1B9.02c
PomBase:SPAC22E12.14c
PomBase:SPAPB18E9.02c
RGD:3395
RGD:3399
RGD:61925
RGD:620968
RGD:67383
SGD:S000000201
UniProtKB:O15530
UniProtKB:P31749
UniProtKB:Q15208
UniProtKB:Q9NRM7
UniProtKB:Q9Y2H1

P

Seeded From UniProt

complete

protected

involved_in

GO:0018105

peptidyl-serine phosphorylation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87986
PANTHER:PTN000683254
RGD:2081
RGD:3395
RGD:3399
RGD:3668
RGD:61925
SGD:S000001609
SGD:S000001861
SGD:S000002898
SGD:S000005460
UniProtKB:A0A1D5PUY5
UniProtKB:P31749
UniProtKB:P41743
UniProtKB:Q02156
UniProtKB:Q05513
UniProtKB:Q05655
WB:WBGene00000102
WB:WBGene00000103
WB:WBGene00004033
WB:WBGene00004034
WB:WBGene00004789
WB:WBGene00006599

P

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003091
FB:FBgn0003744
FB:FBgn0010379
FB:FBgn0260399
FB:FBgn0261854
MGI:MGI:104874
MGI:MGI:2182368
MGI:MGI:87986
MGI:MGI:894676
MGI:MGI:97595
MGI:MGI:97596
MGI:MGI:97599
MGI:MGI:97602
PANTHER:PTN000683254
PomBase:SPAC1B9.02c
PomBase:SPAC22E12.14c
PomBase:SPAC24B11.11c
PomBase:SPAC821.12
PomBase:SPAPB18E9.02c
PomBase:SPCC576.15c
RGD:2081
RGD:2082
RGD:3399
RGD:3668
RGD:620146
RGD:620968
RGD:62390
SGD:S000001248
SGD:S000001609
SGD:S000001861
SGD:S000002898
SGD:S000003324
SGD:S000005105
SGD:S000005460
SGD:S000006315
TAIR:locus:2088515
UniProtKB:O15530
UniProtKB:O95835
UniProtKB:P05771
UniProtKB:P17252
UniProtKB:P31749
UniProtKB:P31751
UniProtKB:P41743
UniProtKB:Q02156
UniProtKB:Q04759
UniProtKB:Q05513
UniProtKB:Q05655
UniProtKB:Q09013
UniProtKB:Q15208
UniProtKB:Q16512
UniProtKB:Q16513
UniProtKB:Q96GX5
UniProtKB:Q9NRM7
UniProtKB:Q9XF67
UniProtKB:Q9Y243
UniProtKB:Q9Y2H1
WB:WBGene00000102
WB:WBGene00000103
WB:WBGene00004034
WB:WBGene00004789
WB:WBGene00006599
dictyBase:DDB_G0268620

F

Seeded From UniProt

complete

protected

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0097473

retinal rod cell apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0090630

activation of GTPase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0090314

positive regulation of protein targeting to membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0072659

protein localization to plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0071486

cellular response to high light intensity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0065002

intracellular protein transmembrane transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0046326

positive regulation of glucose import

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0032869

cellular response to insulin stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

part_of

GO:0032587

ruffle membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

C

Seeded From UniProt

complete

protected

involved_in

GO:0032287

peripheral nervous system myelin maintenance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0031340

positive regulation of vesicle fusion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

involved_in

GO:0006006

glucose metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

part_of

GO:0005938

cell cortex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

C

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

F

Seeded From UniProt

complete

protected

enables

GO:0004672

protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

F

Seeded From UniProt

complete

protected

involved_in

GO:0001934

positive regulation of protein phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q60823
ensembl:ENSMUSP00000103981

P

Seeded From UniProt

complete

protected

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000961
InterPro:IPR017892
InterPro:IPR034677
InterPro:IPR039027

F

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR000961
InterPro:IPR017441
InterPro:IPR017892

F

Seeded From UniProt

complete

protected

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR000961
InterPro:IPR008271
InterPro:IPR017892
InterPro:IPR034677

P

Seeded From UniProt

complete

protected

involved_in

GO:0043491

protein kinase B signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039027

P

Seeded From UniProt

complete

protected

involved_in

GO:0006464

cellular protein modification process

PMID:1409633

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

PMID:1409633
PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion


F

Seeded From UniProt

complete

protected

involved_in

GO:0071156

regulation of cell cycle arrest

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0060644

mammary gland epithelial cell differentiation

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0045444

fat cell differentiation

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0030334

regulation of cell migration

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007165

signal transduction

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:21432781

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-HSA-165182
Reactome:R-HSA-165162
Reactome:R-HSA-109702
Reactome:R-HSA-109700

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-3769394

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

involved_in

GO:0005978

glycogen biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0320

P

Seeded From UniProt

complete

protected

part_of

GO:0005768

endosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

protected

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

protected

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

protected

involved_in

GO:0006006

glucose metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0313

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

protected

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

protected

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

protected

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

protected

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

protected

involved_in

GO:0005977

glycogen metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0321

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

involved_in

GO:0006417

regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0810

P

Seeded From UniProt

complete

protected

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

protected

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

protected

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0762

P

Seeded From UniProt

complete

protected

part_of

GO:0005769

early endosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0094

C

Seeded From UniProt

complete




Cancel