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ZFIN:wnt11
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | wnt11 | |
| Protein Name(s) | wingless-type MMTV integration site family, member 11, | |
| External Links | ||
| ZFIN | ZDB-GENE-990603-12 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000132 |
establishment of mitotic spindle orientation |
ZFIN:ZDB-PUB-040719-4 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050826-1 |
P |
From ZFIN |
||
| GO:0001664 |
G-protein coupled receptor binding |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR12027_AN0 |
F |
From ZFIN |
|||
| GO:0001702 |
gastrulation with mouth forming second |
ZFIN:ZDB-PUB-050607-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1408 |
P |
From ZFIN |
||
| GO:0001702 |
gastrulation with mouth forming second |
ZFIN:ZDB-PUB-051005-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0001702 |
gastrulation with mouth forming second |
ZFIN:ZDB-PUB-970602-19 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0001839 |
neural plate morphogenesis |
ZFIN:ZDB-PUB-060602-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0001947 |
heart looping |
ZFIN:ZDB-PUB-101004-8 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-070316-4 |
P |
From ZFIN |
||
| GO:0005099 |
Ras GTPase activator activity |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0005102 |
receptor binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0005576 |
extracellular region |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From ZFIN |
||
| GO:0005576 |
extracellular region |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0005578 |
proteinaceous extracellular matrix |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0272 |
C |
From ZFIN |
||
| GO:0005578 |
proteinaceous extracellular matrix |
ZFIN:ZDB-PUB-120306-2 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0111 |
C |
From ZFIN |
||
| GO:0005578 |
proteinaceous extracellular matrix |
ZFIN:ZDB-PUB-120306-4 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0111 |
C |
From ZFIN |
||
| GO:0005615 |
extracellular space |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR12027_AN0 |
C |
From ZFIN |
|||
| GO:0005737 |
cytoplasm |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-051005-6 |
IMP: Inferred from Mutant Phenotype |
C |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-061227-6 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0006468 |
protein phosphorylation |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0007275 |
multicellular organismal development |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From ZFIN |
||
| GO:0007275 |
multicellular organismal development |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007417 |
central nervous system development |
ZFIN:ZDB-PUB-970602-19 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0007492 |
endoderm development |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR12027_AN384 |
P |
From ZFIN |
|||
| GO:0007507 |
heart development |
ZFIN:ZDB-PUB-050106-5 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050318-1 |
P |
From ZFIN |
||
| GO:0007507 |
heart development |
ZFIN:ZDB-PUB-050106-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050318-3 |
P |
From ZFIN |
||
| GO:0008078 |
mesodermal cell migration |
ZFIN:ZDB-PUB-080826-15 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0008078 |
mesodermal cell migration |
ZFIN:ZDB-PUB-080826-15 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0008078 |
mesodermal cell migration |
ZFIN:ZDB-PUB-080826-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0008104 |
protein localization |
ZFIN:ZDB-PUB-061227-6 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-990415-223 |
P |
From ZFIN |
||
| GO:0009798 |
axis specification |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR12027_AN0 |
P |
From ZFIN |
|||
| GO:0009952 |
anterior/posterior pattern specification |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR12027_AN0 |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0879 |
P |
From ZFIN |
||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016337 |
cell-cell adhesion |
ZFIN:ZDB-PUB-051005-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0016337 |
cell-cell adhesion |
ZFIN:ZDB-PUB-061227-6 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-990415-223 |
P |
From ZFIN |
||
| GO:0016337 |
cell-cell adhesion |
ZFIN:ZDB-PUB-061227-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070316-4 |
P |
From ZFIN |
||
| GO:0016477 |
cell migration |
ZFIN:ZDB-PUB-970602-19 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0030100 |
regulation of endocytosis |
ZFIN:ZDB-PUB-051005-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0030295 |
protein kinase activator activity |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0030308 |
negative regulation of cell growth |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0030335 |
positive regulation of cell migration |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0030336 |
negative regulation of cell migration |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0032320 |
positive regulation of Ras GTPase activity |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0034394 |
protein localization at cell surface |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0035567 |
non-canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-060602-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-050106-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050318-3 |
P |
From ZFIN |
||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-050718-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-051005-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-060602-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-061020-33 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-080826-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0043010 |
camera-type eye development |
ZFIN:ZDB-PUB-970210-16 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0043010 |
camera-type eye development |
ZFIN:ZDB-PUB-970210-16 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1408 |
P |
From ZFIN |
||
| GO:0043066 |
negative regulation of apoptotic process |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0045859 |
regulation of protein kinase activity |
ZFIN:ZDB-PUB-070711-34 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0048048 |
embryonic eye morphogenesis |
ZFIN:ZDB-PUB-060602-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0048048 |
embryonic eye morphogenesis |
ZFIN:ZDB-PUB-970602-19 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1495 |
P |
From ZFIN |
||
| GO:0048048 |
embryonic eye morphogenesis |
ZFIN:ZDB-PUB-970602-19 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0051496 |
positive regulation of stress fiber assembly |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0060021 |
palate development |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0060026 |
convergent extension |
ZFIN:ZDB-PUB-071009-3 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-080222-4 |
P |
From ZFIN |
||
| GO:0060026 |
convergent extension |
ZFIN:ZDB-PUB-071009-3 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-080222-4 |
P |
From ZFIN |
||
| GO:0060026 |
convergent extension |
ZFIN:ZDB-PUB-071009-3 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-080222-4 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-010904-1 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-100715-12 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-020624-2 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-030408-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-070304-1 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-070304-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-080616-12 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050318-3 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-080826-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070911-1 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-081031-7 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-100302-20 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-100302-20 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-041217-10 |
P |
From ZFIN |
||
| GO:0060031 |
mediolateral intercalation |
ZFIN:ZDB-PUB-000518-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0060031 |
mediolateral intercalation |
ZFIN:ZDB-PUB-000518-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1408 |
P |
From ZFIN |
||
| GO:0060898 |
eye field cell fate commitment involved in camera-type eye formation |
ZFIN:ZDB-PUB-060602-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0061101 |
neuroendocrine cell differentiation |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0070121 |
Kupffer's vesicle development |
ZFIN:ZDB-PUB-101004-8 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-070316-4 |
P |
From ZFIN |
||
| GO:0090037 |
positive regulation of protein kinase C signaling cascade |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-060602-1 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1037 |
P |
From ZFIN |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-110105-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
|
NOT |
GO:0031016 |
pancreas development |
ZFIN:ZDB-PUB-010205-4 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gong Y et al. (2004) Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature 430: 689-93 PubMed GONUTS page
- ↑ Lin F et al. (2005) Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. J Cell Biol 169: 777-87 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Ulrich F et al. (2005) Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev Cell 9: 555-64 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Heisenberg CP & Nüsslein-Volhard C (1997) The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol 184: 85-94 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Cavodeassi F et al. (2005) Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron 47: 43-56 PubMed GONUTS page
- ↑ 6.0 6.1 Oteiza P et al. (2010) Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development 137: 3459-68 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Witzel S et al. (2006) Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. J Cell Biol 175: 791-802 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Matsui T et al. (2005) Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes Dev 19: 164-75 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 Kai M et al. (2008) Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation. Development 135: 3043-51 PubMed GONUTS page
- ↑ Zhu S et al. (2006) RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model for GTPase signaling. Cell Signal 18: 359-72 PubMed GONUTS page
- ↑ Moeller H et al. (2006) Diversin regulates heart formation and gastrulation movements in development. Proc Natl Acad Sci U S A 103: 15900-5 PubMed GONUTS page
- ↑ 12.0 12.1 Heisenberg CP et al. (1996) Genes involved in forebrain development in the zebrafish, Danio rerio. Development 123: 191-203 PubMed GONUTS page
- ↑ Lemeer S et al. (2007) Protein-tyrosine kinase activity profiling in knock down zebrafish embryos. PLoS One 2: e581 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Gerdes JM et al. (2007) Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nat Genet 39: 1350-60 PubMed GONUTS page
- ↑ Topczewski J et al. (2001) The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell 1: 251-64 PubMed GONUTS page
- ↑ Marlow F et al. (2002) Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements. Curr Biol 12: 876-84 PubMed GONUTS page
- ↑ Kilian B et al. (2003) The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mech Dev 120: 467-76 PubMed GONUTS page
- ↑ 18.0 18.1 Jopling C & den Hertog J (2005) Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements. EMBO Rep 6: 426-31 PubMed GONUTS page
- ↑ Yao S et al. (2008) Pnas4 is a novel regulator for convergence and extension during vertebrate gastrulation. FEBS Lett 582: 2325-32 PubMed GONUTS page
- ↑ Ferrante MI et al. (2009) Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Hum Mol Genet 18: 289-303 PubMed GONUTS page
- ↑ 21.0 21.1 van Eekelen M et al. (2010) RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation. Dev Biol 340: 626-39 PubMed GONUTS page
- ↑ 22.0 22.1 Heisenberg CP et al. (2000) Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405: 76-81 PubMed GONUTS page
- ↑ Biemar F et al. (2001) Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Dev Biol 230: 189-203 PubMed GONUTS page