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ZFIN:vangl2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) vangl2
Protein Name(s) vang-like 2 (van gogh, Drosophila),
External Links
ZFIN ZDB-GENE-020507-3

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000132

establishment of mitotic spindle orientation

ZFIN:ZDB-PUB-040719-4
PMID:15254551[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0000902

cell morphogenesis

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0001736

establishment of planar polarity

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-020114-1
PMID:11820812[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-030728-18
PMID:12874125[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-030724-5

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-081121-15
PMID:19013446[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-051128-5

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-081121-15
PMID:19013446[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-060119-1

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-081121-15
PMID:19013446[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0001839

neural plate morphogenesis

ZFIN:ZDB-PUB-060313-5
PMID:16502420[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0001841

neural tube formation

ZFIN:ZDB-PUB-060124-10
PMID:16407953[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1083

P

From ZFIN

GO:0003401

axis elongation

ZFIN:ZDB-PUB-110518-11
PMID:21498478[8]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-110808-1

P

From ZFIN

GO:0003401

axis elongation

ZFIN:ZDB-PUB-110518-11
PMID:21498478[8]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-110808-1

P

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-020219-18
PMID:11780127[9]

IPI: Inferred from Physical Interaction

UniProtKB:P51142

F

From ZFIN

GO:0005623

cell

ZFIN:ZDB-PUB-040719-4
PMID:15254551[1]

IMP: Inferred from Mutant Phenotype

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q90X64

C

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

P

From ZFIN

GO:0007369

gastrulation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0306

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From ZFIN

GO:0014812

muscle cell migration

ZFIN:ZDB-PUB-070920-4
PMID:17849437[10]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

From ZFIN

GO:0014812

muscle cell migration

ZFIN:ZDB-PUB-070920-4
PMID:17849437[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

C

From ZFIN

GO:0016055

Wnt receptor signaling pathway

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From ZFIN

GO:0021535

cell migration in hindbrain

ZFIN:ZDB-PUB-070330-43
PMID:17392791[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

From ZFIN

GO:0030010

establishment of cell polarity

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030154

cell differentiation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From ZFIN

GO:0030903

notochord development

ZFIN:ZDB-PUB-970210-10
PMID:9007234[12]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[13]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070308-4
ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[13]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080422-2
ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0042074

cell migration involved in gastrulation

ZFIN:ZDB-PUB-020219-18
PMID:11780127[9]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0042074

cell migration involved in gastrulation

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0042074

cell migration involved in gastrulation

ZFIN:ZDB-PUB-030728-18
PMID:12874125[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-263
ZFIN:ZDB-MRPHLNO-060209-7

P

From ZFIN

GO:0042074

cell migration involved in gastrulation

ZFIN:ZDB-PUB-050513-4
PMID:15882862[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-1

P

From ZFIN

GO:0042074

cell migration involved in gastrulation

ZFIN:ZDB-PUB-050513-4
PMID:15882862[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-4

P

From ZFIN

GO:0045813

positive regulation of Wnt receptor signaling pathway, calcium modulating pathway

ZFIN:ZDB-PUB-020219-18
PMID:11780127[9]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048048

embryonic eye morphogenesis

ZFIN:ZDB-PUB-970602-19
PMID:9142986[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1037

P

From ZFIN

GO:0055002

striated muscle cell development

ZFIN:ZDB-PUB-070920-4
PMID:17849437[10]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

From ZFIN

GO:0055002

striated muscle cell development

ZFIN:ZDB-PUB-070920-4
PMID:17849437[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

From ZFIN

GO:0060026

convergent extension

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0060026

convergent extension

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0060026

convergent extension

ZFIN:ZDB-PUB-070210-25
PMID:17239849[16]

IPI: Inferred from Physical Interaction

UniProtKB:Q90Z52

P

From ZFIN

GO:0060026

convergent extension

ZFIN:ZDB-PUB-080218-2
PMID:18195109[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080416-1

P

From ZFIN

GO:0060026

convergent extension

ZFIN:ZDB-PUB-100105-38
PMID:20043994[18]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-001026-7
PMID:10992326[19]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-030728-18
PMID:12874125[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-030724-5

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-070210-25
PMID:17239849[16]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-011119-1
ZFIN:ZDB-GENO-070906-2

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-080630-16
PMID:18582857[20]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-081212-1

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-081031-7
PMID:18971206[21]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-090312-2

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-081031-7
PMID:18971206[21]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-090312-2

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-970210-12
PMID:9007236[22]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-970210-6
PMID:9007230[23]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060070

canonical Wnt receptor signaling pathway

ZFIN:ZDB-PUB-020219-18
PMID:11780127[9]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

ZFIN:ZDB-PUB-020219-18
PMID:11780127[9]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

ZFIN:ZDB-PUB-020716-20
PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN


edit table

Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ 1.0 1.1 Gong Y et al. (2004) Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature 430: 689-93 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Jessen JR et al. (2002) Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol 4: 610-5 PubMed GONUTS page
  3. ↑ Bingham S et al. (2002) The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Dev Biol 242: 149-60 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 Carreira-Barbosa F et al. (2003) Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development 130: 4037-46 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 Sittaramane V et al. (2009) The cell adhesion molecule Tag1, transmembrane protein Stbm/Vangl2, and Lamininalpha1 exhibit genetic interactions during migration of facial branchiomotor neurons in zebrafish. Dev Biol 325: 363-73 PubMed GONUTS page
  6. ↑ Takamiya M & Campos-Ortega JA (2006) Hedgehog signalling controls zebrafish neural keel morphogenesis via its level-dependent effects on neurogenesis. Dev Dyn 235: 978-97 PubMed GONUTS page
  7. ↑ Ciruna B et al. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 439: 220-4 PubMed GONUTS page
  8. ↑ 8.0 8.1 Burcklé C et al. (2011) Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros. Hum Mol Genet 20: 2611-27 PubMed GONUTS page
  9. ↑ 9.0 9.1 9.2 9.3 9.4 Park M & Moon RT (2002) The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nat Cell Biol 4: 20-5 PubMed GONUTS page
  10. ↑ 10.0 10.1 10.2 10.3 Yin C & Solnica-Krezel L (2007) Convergence and extension movements affect dynamic notochord-somite interactions essential for zebrafish slow muscle morphogenesis. Dev Dyn 236: 2742-56 PubMed GONUTS page
  11. ↑ Tawk M et al. (2007) A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature 446: 797-800 PubMed GONUTS page
  12. ↑ Stemple DL et al. (1996) Mutations affecting development of the notochord in zebrafish. Development 123: 117-28 PubMed GONUTS page
  13. ↑ 13.0 13.1 13.2 Harrington MJ et al. (2007) Cadherin-mediated adhesion regulates posterior body formation. BMC Dev Biol 7: 130 PubMed GONUTS page
  14. ↑ 14.0 14.1 Formstone CJ & Mason I (2005) Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Dev Biol 282: 320-35 PubMed GONUTS page
  15. ↑ Heisenberg CP & Nüsslein-Volhard C (1997) The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol 184: 85-94 PubMed GONUTS page
  16. ↑ 16.0 16.1 Yin C & Solnica-Krezel L (2007) Convergence and extension movements mediate the specification and fate maintenance of zebrafish slow muscle precursors. Dev Biol 304: 141-55 PubMed GONUTS page
  17. ↑ Yin C et al. (2008) Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation. J Cell Biol 180: 221-32 PubMed GONUTS page
  18. ↑ Reynolds A et al. (2010) VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mech Dev 127: 385-92 PubMed GONUTS page
  19. ↑ Sepich DS et al. (2000) Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis 27: 159-73 PubMed GONUTS page
  20. ↑ Vervenne HB et al. (2008) Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Dev Biol 320: 267-77 PubMed GONUTS page
  21. ↑ 21.0 21.1 Ferrante MI et al. (2009) Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Hum Mol Genet 18: 289-303 PubMed GONUTS page
  22. ↑ Hammerschmidt M et al. (1996) Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development 123: 143-51 PubMed GONUTS page
  23. ↑ Solnica-Krezel L et al. (1996) Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development 123: 67-80 PubMed GONUTS page
Retrieved from "http://gowiki.tamu.edu/wiki/index.php/ZFIN:vangl2"
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