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ZFIN:ttll6

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) ttll6
Protein Name(s) tubulin tyrosine ligase-like family, member 6,
External Links
ZFIN ZDB-GENE-080107-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003341

cilium movement

ZFIN:ZDB-PUB-110131-16
PMID:21262966[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-110628-6
ZFIN:ZDB-MRPHLNO-110628-7

P

From ZFIN

GO:0004835

tubulin-tyrosine ligase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004344

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From ZFIN

GO:0005856

cytoskeleton

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From ZFIN

GO:0005929

cilium

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0969

C

From ZFIN

GO:0005929

cilium

ZFIN:ZDB-PUB-110131-16
PMID:21262966[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0006464

protein modification process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004344

P

From ZFIN

GO:0015631

tubulin binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:A4Q9E8

F

From ZFIN

GO:0016874

ligase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

From ZFIN

GO:0018095

protein polyglutamylation

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:A4Q9E8

P

From ZFIN

GO:0018095

protein polyglutamylation

ZFIN:ZDB-PUB-110128-8
PMID:21074048[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:A4Q9E8

P

From ZFIN

GO:0018095

protein polyglutamylation

ZFIN:ZDB-PUB-120117-22
PMID:22246503[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030030

cell projection organization

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0970

P

From ZFIN

GO:0035083

cilium axoneme assembly

ZFIN:ZDB-PUB-070907-22
PMID:17761526[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080107-1

P

From ZFIN

GO:0035083

cilium axoneme assembly

ZFIN:ZDB-PUB-110131-16
PMID:21262966[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-110628-6
ZFIN:ZDB-MRPHLNO-110628-7

P

From ZFIN

GO:0035083

cilium axoneme assembly

ZFIN:ZDB-PUB-120117-22
PMID:22246503[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110628-7

P

From ZFIN

GO:0036064

cilium basal body

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8N841

C

From ZFIN

GO:0042995

cell projection

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From ZFIN

GO:0070740

tubulin-glutamic acid ligase activity

ZFIN:ZDB-PUB-110131-16
PMID:21262966[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110628-7

F

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Pathak N et al. (2011) Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility. J Biol Chem 286: 11685-95 PubMed GONUTS page
  2. Rogowski K et al. (2010) A family of protein-deglutamylating enzymes associated with neurodegeneration. Cell 143: 564-78 PubMed GONUTS page
  3. 3.0 3.1 Lee JE et al. (2012) CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium. Nat Genet 44: 193-9 PubMed GONUTS page
  4. Pathak N et al. (2007) The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation. Mol Biol Cell 18: 4353-64 PubMed GONUTS page
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