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ZFIN:tp73

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) tp73
Protein Name(s) tumor protein p73,
External Links
ZFIN ZDB-GENE-030814-2

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0000785

chromatin

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

C

From ZFIN

GO:0002039

p53 binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002117

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

F

From ZFIN

GO:0003682

chromatin binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

F

From ZFIN

GO:0003684

damaged DNA binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

F

From ZFIN

GO:0003690

double-stranded DNA binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002117

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008967

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-041116-1
PMID:15541366[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002117

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

C

From ZFIN

GO:0005667

transcription factor complex

ZFIN:ZDB-PUB-041116-1
PMID:15541366[1]

IC: Inferred by Curator

GO:0003700

C

From ZFIN

GO:0005667

transcription factor complex

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

C

From ZFIN

GO:0005829

cytosol

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

C

From ZFIN

GO:0006351

transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002117

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008967

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-041116-1
PMID:15541366[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0006915

apoptotic process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002117

P

From ZFIN

GO:0006978

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0010165

response to X-ray

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0010332

response to gamma radiation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0031571

mitotic cell cycle G1/S transition DNA damage checkpoint

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0034644

cellular response to UV

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0042771

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

P

From ZFIN

GO:0043508

negative regulation of JUN kinase activity

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN31

P

From ZFIN

GO:0043524

negative regulation of neuron apoptotic process

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN31

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11447_AN0

F

From ZFIN

GO:0044212

transcription regulatory region DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR011615

F

From ZFIN

GO:0048701

embryonic cranial skeleton morphogenesis

ZFIN:ZDB-PUB-080422-7
PMID:18418056[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050107-2

P

From ZFIN

GO:0051262

protein tetramerization

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR010991

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Satoh S et al. (2004) Identification of a novel splicing form of zebrafish p73 having a strong transcriptional activity. Biochem Biophys Res Commun 325: 835-42 PubMed GONUTS page
  2. Davidson W et al. (2008) Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos. Cell Cycle 7: 1224-30 PubMed GONUTS page
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