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ZFIN:szl

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) szl
Protein Name(s) sizzled,
External Links
ZFIN ZDB-GENE-030530-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001944

vasculature development

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

P

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IPI: Inferred from Physical Interaction

ZFIN:ZDB-GENE-041020-1

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IPI: Inferred from Physical Interaction

ZFIN:ZDB-GENE-060818-1

F

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

C

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

P

From ZFIN

GO:0008406

gonad development

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

P

From ZFIN

GO:0009790

embryo development

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-020605-7
PMID:11969259[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060811-11

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-9
ZFIN:ZDB-MRPHLNO-060818-1
ZFIN:ZDB-MRPHLNO-060818-2

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-060818-1
ZFIN:ZDB-MRPHLNO-060818-2

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-080212-1
PMID:16890217[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-060818-2
ZFIN:ZDB-MRPHLNO-080212-1

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-080212-1
PMID:16890217[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060818-2

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-101011-38
PMID:20886103[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-9
ZFIN:ZDB-MRPHLNO-060818-1
ZFIN:ZDB-MRPHLNO-060818-2

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-101011-38
PMID:20886103[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0016055

Wnt receptor signaling pathway

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From ZFIN

GO:0017147

Wnt-protein binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

F

From ZFIN

GO:0030165

PDZ domain binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

F

From ZFIN

GO:0030514

negative regulation of BMP signaling pathway

ZFIN:ZDB-PUB-990920-2
PMID:10491258[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0042813

Wnt-activated receptor activity

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

F

From ZFIN

GO:0048263

determination of dorsal identity

ZFIN:ZDB-PUB-041108-1
PMID:15525664[6]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-020812-3

P

From ZFIN

GO:0048263

determination of dorsal identity

ZFIN:ZDB-PUB-041108-1
PMID:15525664[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060811-11

P

From ZFIN

GO:0048263

determination of dorsal identity

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060811-11

P

From ZFIN

GO:0048263

determination of dorsal identity

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060818-2

P

From ZFIN

GO:0050821

protein stabilization

ZFIN:ZDB-PUB-060315-3
PMID:16518392[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0060070

canonical Wnt receptor signaling pathway

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN0

P

From ZFIN

NOT

GO:0042995

cell projection

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11309_AN382

C

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Muraoka O et al. (2006) Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin protein. Nat Cell Biol 8: 329-38 PubMed GONUTS page
  2. Wagner DS & Mullins MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev Biol 245: 109-23 PubMed GONUTS page
  3. 3.0 3.1 Dal-Pra S et al. (2006) Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Dev Biol 298: 514-26 PubMed GONUTS page
  4. 4.0 4.1 Zhang JL et al. (2010) Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One 5: e12846 PubMed GONUTS page
  5. Miller-Bertoglio V et al. (1999) Maternal and zygotic activity of the zebrafish ogon locus antagonizes BMP signaling. Dev Biol 214: 72-86 PubMed GONUTS page
  6. 6.0 6.1 Little SC & Mullins MC (2004) Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development 131: 5825-35 PubMed GONUTS page
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