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ZFIN:spaw

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) spaw
Protein Name(s) southpaw,
External Links
ZFIN ZDB-GENE-030219-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001947

heart looping

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0001947

heart looping

ZFIN:ZDB-PUB-100730-1

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060608-121

P

From ZFIN

GO:0003140

determination of left/right asymmetry in lateral mesoderm

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0003140

determination of left/right asymmetry in lateral mesoderm

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0003140

determination of left/right asymmetry in lateral mesoderm

ZFIN:ZDB-PUB-040405-3
PMID:15084459[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060718-1

P

From ZFIN

GO:0003146

heart jogging

ZFIN:ZDB-PUB-080915-18
PMID:18784369[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-2

P

From ZFIN

GO:0005576

extracellular region

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From ZFIN

GO:0005576

extracellular region

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002405

C

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-031103-19
PMID:14576439[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-051012-8
PMID:16207761[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-070711-5
PMID:17592620[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-070813-9
PMID:17678853[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-080309-9
PMID:18267096[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-080915-18
PMID:18784369[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-2

P

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001839

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017948

F

From ZFIN

GO:0035050

embryonic heart tube development

ZFIN:ZDB-PUB-080309-9
PMID:18267096[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0035462

determination of left/right asymmetry in diencephalon

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0035462

determination of left/right asymmetry in diencephalon

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0035469

determination of pancreatic left/right asymmetry

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0035469

determination of pancreatic left/right asymmetry

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN

GO:0040007

growth

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

From ZFIN

GO:0048368

lateral mesoderm development

ZFIN:ZDB-PUB-081110-6
PMID:18985756[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:0060971

embryonic heart tube left/right pattern formation

ZFIN:ZDB-PUB-100730-1

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060608-121

P

From ZFIN

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

From ZFIN

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

ZFIN:ZDB-PUB-030425-22
PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Long S et al. (2003) The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry. Development 130: 2303-16 PubMed GONUTS page
  2. Hashimoto H et al. (2004) The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish. Development 131: 1741-53 PubMed GONUTS page
  3. 3.0 3.1 Baker K et al. (2008) Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. Proc Natl Acad Sci U S A 105: 13924-9 PubMed GONUTS page
  4. Horne-Badovinac S et al. (2003) A cellular framework for gut-looping morphogenesis in zebrafish. Science 302: 662-5 PubMed GONUTS page
  5. Gamse JT et al. (2005) Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target. Development 132: 4869-81 PubMed GONUTS page
  6. Kuan YS et al. (2007) Selective asymmetry in a conserved forebrain to midbrain projection. J Exp Zool B Mol Dev Evol 308: 669-78 PubMed GONUTS page
  7. Carl M et al. (2007) Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries. Neuron 55: 393-405 PubMed GONUTS page
  8. 8.0 8.1 Smith KA et al. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev Cell 14: 287-97 PubMed GONUTS page
  9. Wang X & Yost HJ (2008) Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev Dyn 237: 3640-7 PubMed GONUTS page
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