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ZFIN:runx2b

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) runx2b
Protein Name(s) runt-related transcription factor 2b,
External Links
ZFIN ZDB-GENE-040629-4

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002062

chondrocyte differentiation

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-8

P

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000040

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013524

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008967

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013524

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-040721-6
PMID:15261836[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q08775

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-040721-6
PMID:15261836[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q13950

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-050714-6
PMID:16007341[3]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000040

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000040

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

C

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000040

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008967

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012346

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013524

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-111122-21
PMID:22087291[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-061127-3
ZFIN:ZDB-MRPHLNO-111209-6

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-111122-21
PMID:22087291[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-061127-3
ZFIN:ZDB-MRPHLNO-111209-7

P

From ZFIN

GO:0042809

vitamin D receptor binding

ZFIN:ZDB-PUB-110204-3
PMID:20236534[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9PTN2

F

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-050714-6
PMID:16007341[3]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-080227-3
PMID:18246063[6]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0051216

cartilage development

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-1

P

From ZFIN

GO:0051216

cartilage development

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-2

P

From ZFIN

GO:0051216

cartilage development

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-3

P

From ZFIN

GO:0051216

cartilage development

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-4

P

From ZFIN

GO:0051216

cartilage development

ZFIN:ZDB-PUB-061020-9
PMID:17013873[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-061127-8

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Flores MV et al. (2006) A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish. Dev Dyn 235: 3166-76 PubMed GONUTS page
  2. 2.0 2.1 Flores MV et al. (2004) Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements. Gene Expr Patterns 4: 573-81 PubMed GONUTS page
  3. 3.0 3.1 Pinto JP et al. (2005) Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro. J Bone Miner Res 20: 1440-53 PubMed GONUTS page
  4. 4.0 4.1 Yang DC et al. (2011) Twist controls skeletal development and dorsoventral patterning by regulating runx2 in zebrafish. PLoS One 6: e27324 PubMed GONUTS page
  5. Marcellini S et al. (2010) Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis. BMC Evol Biol 10: 78 PubMed GONUTS page
  6. Flores MV et al. (2008) Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish. Nat Cell Biol 10: 346-52 PubMed GONUTS page
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