![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
ZFIN:runx1
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | runx1 | |
| Protein Name(s) | runt-related transcription factor 1, | |
| External Links | ||
| ZFIN | ZDB-GENE-000605-1 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001568 |
blood vessel development |
ZFIN:ZDB-PUB-020410-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-1 |
P |
From ZFIN |
||
| GO:0001568 |
blood vessel development |
ZFIN:ZDB-PUB-020410-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-2 |
P |
From ZFIN |
||
| GO:0003677 |
DNA binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0003677 |
DNA binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0003677 |
DNA binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0005524 |
ATP binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0005634 |
nucleus |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0005634 |
nucleus |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007399 |
nervous system development |
ZFIN:ZDB-PUB-020410-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-1 |
P |
From ZFIN |
||
| GO:0007399 |
nervous system development |
ZFIN:ZDB-PUB-020410-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-2 |
P |
From ZFIN |
||
| GO:0010628 |
positive regulation of gene expression |
ZFIN:ZDB-PUB-090318-8 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-010611-1 |
P |
From ZFIN |
||
| GO:0010628 |
positive regulation of gene expression |
ZFIN:ZDB-PUB-090318-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-1 |
P |
From ZFIN |
||
| GO:0030097 |
hemopoiesis |
ZFIN:ZDB-PUB-050303-2 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050726-3 |
P |
From ZFIN |
||
| GO:0030097 |
hemopoiesis |
ZFIN:ZDB-PUB-070625-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050726-3 |
P |
From ZFIN |
||
| GO:0030097 |
hemopoiesis |
ZFIN:ZDB-PUB-100223-24 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-091020-2 |
P |
From ZFIN |
||
| GO:0030099 |
myeloid cell differentiation |
ZFIN:ZDB-PUB-090318-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-1 |
P |
From ZFIN |
||
| GO:0030099 |
myeloid cell differentiation |
ZFIN:ZDB-PUB-111205-10 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-120220-7 |
P |
From ZFIN |
||
| GO:0035162 |
embryonic hemopoiesis |
ZFIN:ZDB-PUB-020410-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-060207-2 |
P |
From ZFIN |
||
| GO:0035162 |
embryonic hemopoiesis |
ZFIN:ZDB-PUB-050920-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051102-3 |
P |
From ZFIN |
||
| GO:0043565 |
sequence-specific DNA binding |
ZFIN:ZDB-PUB-090318-8 |
IPI: Inferred from Physical Interaction |
ZFIN:ZDB-GENE-020515-2 |
F |
From ZFIN |
||
| GO:0060216 |
definitive hemopoiesis |
ZFIN:ZDB-PUB-081022-37 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-100813-4 |
P |
From ZFIN |
||
| GO:0060216 |
definitive hemopoiesis |
ZFIN:ZDB-PUB-090204-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-091020-2 |
P |
From ZFIN |
||
| GO:0060216 |
definitive hemopoiesis |
ZFIN:ZDB-PUB-090204-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051102-3 |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Kalev-Zylinska ML et al. (2002) Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis. Development 129: 2015-30 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kitaguchi T et al. (2009) Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis. Mech Dev 126: 314-23 PubMed GONUTS page
- ↑ Gering M & Patient R (2005) Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos. Dev Cell 8: 389-400 PubMed GONUTS page
- ↑ Zhang XY & Rodaway AR (2007) SCL-GFP transgenic zebrafish: in vivo imaging of blood and endothelial development and identification of the initial site of definitive hematopoiesis. Dev Biol 307: 179-94 PubMed GONUTS page
- ↑ Sood R et al. (2010) Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation. Blood 115: 2806-9 PubMed GONUTS page
- ↑ Ma N et al. (2011) Characterization of a weak allele of zebrafish cloche mutant. PLoS One 6: e27540 PubMed GONUTS page
- ↑ Burns CE et al. (2005) Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev 19: 2331-42 PubMed GONUTS page
- ↑ Lam EY et al. (2009) Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors. Blood 113: 1241-9 PubMed GONUTS page
- ↑ 9.0 9.1 Jin H et al. (2009) Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI. Development 136: 647-54 PubMed GONUTS page
abde |
hmnp |
rs |