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ZFIN:ptenb

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) ptenb
Protein Name(s) phosphatase and tensin homolog B,
External Links
ZFIN ZDB-GENE-030616-47

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000287

magnesium ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

F

From ZFIN

GO:0001568

blood vessel development

ZFIN:ZDB-PUB-050930-12
PMID:16193492[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0004725

protein tyrosine phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

F

From ZFIN

GO:0004725

protein tyrosine phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

F

From ZFIN

GO:0006470

protein dephosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000340

P

From ZFIN

GO:0006470

protein dephosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0008138

protein tyrosine/serine/threonine phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000340

F

From ZFIN

GO:0008285

negative regulation of cell proliferation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0016311

dephosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

P

From ZFIN

GO:0016314

phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

F

From ZFIN

GO:0016791

phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

F

From ZFIN

GO:0030097

hemopoiesis

ZFIN:ZDB-PUB-100408-31
PMID:20371743[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0030165

PDZ domain binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

F

From ZFIN

GO:0030336

negative regulation of cell migration

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0031174

lifelong otolith mineralization

ZFIN:ZDB-PUB-050930-12
PMID:16193492[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0031647

regulation of protein stability

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0042577

lipid phosphatase activity

ZFIN:ZDB-PUB-050930-12
PMID:16193492[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

F

From ZFIN

GO:0042577

lipid phosphatase activity

ZFIN:ZDB-PUB-070827-3
PMID:17704803[3]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0046855

inositol phosphate dephosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0046856

phosphatidylinositol dephosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0046856

phosphatidylinositol dephosphorylation

ZFIN:ZDB-PUB-050930-12
PMID:16193492[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0046856

phosphatidylinositol dephosphorylation

ZFIN:ZDB-PUB-070827-3
PMID:17704803[3]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0051800

phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

F

From ZFIN

GO:0051895

negative regulation of focal adhesion assembly

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0051896

regulation of protein kinase B signaling cascade

ZFIN:ZDB-PUB-050930-12
PMID:16193492[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0051898

negative regulation of protein kinase B signaling cascade

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017361

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-110518-6
PMID:21494560[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080910-4
ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-110518-6
PMID:21494560[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-7

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-110518-6
PMID:21494560[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060214-8

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Croushore JA et al. (2005) Ptena and ptenb genes play distinct roles in zebrafish embryogenesis. Dev Dyn 234: 911-21 PubMed GONUTS page
  2. Fu CT et al. (2010) An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 axis controls myeloid development and transformation. Blood 115: 4715-24 PubMed GONUTS page
  3. 3.0 3.1 Faucherre A et al. (2008) Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. Oncogene 27: 1079-86 PubMed GONUTS page
  4. 4.0 4.1 4.2 Yeh CM et al. (2011) Ptenb mediates gastrulation cell movements via Cdc42/AKT1 in zebrafish. PLoS One 6: e18702 PubMed GONUTS page
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