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ZFIN:ptc1

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) ptc1
Protein Name(s) patched 1,
External Links
ZFIN ZDB-GENE-980526-44

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

From ZFIN

GO:0007224

smoothened signaling pathway

ZFIN:ZDB-PUB-090324-16
PMID:19305393[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050308-1

P

From ZFIN

GO:0008158

hedgehog receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR003392

F

From ZFIN

GO:0008158

hedgehog receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004766

F

From ZFIN

GO:0009954

proximal/distal pattern formation

ZFIN:ZDB-PUB-080519-2
PMID:18479681[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080327-300

P

From ZFIN

GO:0009954

proximal/distal pattern formation

ZFIN:ZDB-PUB-080519-2
PMID:18479681[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050308-1

P

From ZFIN

GO:0010002

cardioblast differentiation

ZFIN:ZDB-PUB-081022-5
PMID:18842815[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080728-6

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR003392

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000731

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004766

C

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-848

P

From ZFIN

GO:0043010

camera-type eye development

ZFIN:ZDB-PUB-080519-2
PMID:18479681[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080327-300

P

From ZFIN

GO:0043010

camera-type eye development

ZFIN:ZDB-PUB-080519-2
PMID:18479681[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050308-1

P

From ZFIN

GO:0048635

negative regulation of muscle organ development

ZFIN:ZDB-PUB-060616-49
PMID:16765934[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-030131-4827

P

From ZFIN

GO:0048635

negative regulation of muscle organ development

ZFIN:ZDB-PUB-060616-49
PMID:16765934[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050308-3
ZFIN:ZDB-MRPHLNO-061130-1
ZFIN:ZDB-MRPHLNO-061130-2

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Wilson CW et al. (2009) Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature 459: 98-102 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Lee J et al. (2008) Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye. Dev Biol 319: 10-22 PubMed GONUTS page
  3. Thomas NA et al. (2008) Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential. Development 135: 3789-99 PubMed GONUTS page
  4. Karlstrom RO et al. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123: 427-38 PubMed GONUTS page
  5. 5.0 5.1 Ochi H et al. (2006) Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened. Dev Biol 297: 127-40 PubMed GONUTS page
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